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NCT06572384 · ClinicalTrials.gov registry record · Phase 3

A Study of the Efficacy and Safety of Belimumab in Adults With Interstitial Lung Disease Associated With Connective Tissue Disease

A Phase 3 study of Lung Diseases, Interstitial, sponsored by GlaxoSmithKline.

Recruiting
Registry status
Phase 3
Development phase
440
Enrollment target
20
Study locations

NCT06572384 is a Phase 3 study of Lung Diseases, Interstitial that is actively recruiting participants, run by GlaxoSmithKline. The registered enrollment target is 440 participants, below the 12,465-participant average among 10 other Lung Diseases, Interstitial trials with a reported enrollment target (96% lower). The trial reports 20 study locations across 9 states.

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The verdict

NCT06572384, a Phase 3 study of Lung Diseases, Interstitial, is actively recruiting participants, sponsored by GlaxoSmithKline.

RECRUITING
Registry status
Phase 3
Development phase
440 participants
Enrollment target
20
Study locations

Study Summary

Interstitial lung disease (ILD) is a lung condition resulting in inflammation and stiffening of the lung, often associated with connective tissue diseases (CTDs). ILD causes reduction in lung volume, shortness of breath, cough and fatigue therefore has high impact on quality of life and is also the leading cause of death in participants with these conditions. The study will assess whether treatment of CTD-ILD participants with belimumab in addition to standard therapy will result in the stabilization and/or improvement of lung function and improve symptoms associated with ILD with an acceptable safety profile.

Interventions

  • OTHER Placebo
  • BIOLOGICAL Belimumab

Study Locations (20)

California

  • GSK Investigational Site - Los Angeles
  • GSK Investigational Site - Los Angeles
  • GSK Investigational Site - Los Angeles
  • GSK Investigational Site - San Francisco
  • GSK Investigational Site - Upland

Other

  • GSK Investigational Site - Buenos Aires
  • GSK Investigational Site - Buenos Aires
  • GSK Investigational Site - Buenos Aires
  • GSK Investigational Site - Ciudad Autonoma Buenos Aires

New York

  • GSK Investigational Site - New York
  • GSK Investigational Site - New York
  • GSK Investigational Site - Potsdam

Florida

  • GSK Investigational Site - Gainesville
  • GSK Investigational Site - Naples

Texas

  • GSK Investigational Site - Houston
  • GSK Investigational Site - Temple

Missouri

  • GSK Investigational Site - St Louis

North Carolina

  • GSK Investigational Site - Durham

Pennsylvania

  • GSK Investigational Site - Philadelphia

Trial Details

FieldValue
Enrollment Target 440 participants
Start Date 2024-09-11
Est. Completion 2028-12-13
Phase Phase 3

Sponsor

GlaxoSmithKline

1,345 total trials

What the Registry Record Tells You About NCT06572384

The ClinicalTrials.gov registry entry for NCT06572384 describes a study currently listed as recruiting, categorized as Phase 3. The registered enrollment target is 440 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 12,465-participant average among 10 other Lung Diseases, Interstitial trials with a reported enrollment target (96% lower). The listed sponsor is GlaxoSmithKline, which has 1,345 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Lung Diseases, Interstitial appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT06572384 reports 20 study locations spanning 9 distinct geographic areas - top geographies include California, Other, New York.

Frequently Asked Questions

What is clinical trial NCT06572384 about?

NCT06572384 is a clinical study titled "A Study of the Efficacy and Safety of Belimumab in Adults With Interstitial Lung Disease Associated With Connective Tissue Disease". Interstitial lung disease (ILD) is a lung condition resulting in inflammation and stiffening of the lung, often associated with connective tissue diseases (CTDs). ILD causes reduction in lung volume, shortness of breath, cough and fatigue therefore has high impact on quality of life and is also the ...

What is the current status of trial NCT06572384?

This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 440 participants. The study started on 2024-09-11. Estimated completion is 2028-12-13.

What conditions does trial NCT06572384 study?

This clinical trial studies the following conditions: Lung Diseases, Interstitial.

What interventions are being tested in trial NCT06572384?

The interventions under investigation include: Placebo (OTHER), Belimumab (BIOLOGICAL).

Who is sponsoring clinical trial NCT06572384?

This trial is sponsored by GlaxoSmithKline, which has 1,345 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06572384 being conducted?

This trial has 20 study locations across California, Florida, Missouri, New York, North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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