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A Study of the Efficacy and Safety of Belimumab in Adults With Interstitial Lung Disease Associated With Connective Tissue Disease
NCT06572384 · View on ClinicalTrials.gov ↗
Study Summary
Interstitial lung disease (ILD) is a lung condition resulting in inflammation and stiffening of the lung, often associated with connective tissue diseases (CTDs). ILD causes reduction in lung volume, shortness of breath, cough and fatigue therefore has high impact on quality of life and is also the leading cause of death in participants with these conditions. The study will assess whether treatment of CTD-ILD participants with belimumab in addition to standard therapy will result in the stabilization and/or improvement of lung function and improve symptoms associated with ILD with an acceptable safety profile.
Conditions Studied
Interventions
- OTHER Placebo
- BIOLOGICAL Belimumab
Study Locations (20)
California
- GSK Investigational Site — Los Angeles
- GSK Investigational Site — Los Angeles
- GSK Investigational Site — Los Angeles
- GSK Investigational Site — San Francisco
- GSK Investigational Site — Upland
Other
- GSK Investigational Site — Buenos Aires
- GSK Investigational Site — Buenos Aires
- GSK Investigational Site — Buenos Aires
- GSK Investigational Site — Ciudad Autonoma Buenos Aires
New York
- GSK Investigational Site — New York
- GSK Investigational Site — New York
- GSK Investigational Site — Potsdam
Florida
- GSK Investigational Site — Gainesville
- GSK Investigational Site — Naples
Texas
- GSK Investigational Site — Houston
- GSK Investigational Site — Temple
Missouri
- GSK Investigational Site — St Louis
North Carolina
- GSK Investigational Site — Durham
Pennsylvania
- GSK Investigational Site — Philadelphia
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 440 participants |
| Start Date | 2024-09-11 |
| Est. Completion | 2028-12-13 |
| Phase | Phase 3 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06572384
The ClinicalTrials.gov registry entry for NCT06572384 describes a study currently listed as recruiting. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 440 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is GlaxoSmithKline, which has 558 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Lung Diseases, Interstitial appearing as the primary indexed condition, and to 2 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT06572384 reports 20 study locations spanning 9 distinct geographic areas — top geographies include California, Other, New York. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT06572384 about?
NCT06572384 is a clinical study titled "A Study of the Efficacy and Safety of Belimumab in Adults With Interstitial Lung Disease Associated With Connective Tissue Disease". Interstitial lung disease (ILD) is a lung condition resulting in inflammation and stiffening of the lung, often associated with connective tissue diseases (CTDs). ILD causes reduction in lung volume, shortness of breath, cough and fatigue therefore has high impact on quality of life and is also the ...
What is the current status of trial NCT06572384?
This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 440 participants. The study started on 2024-09-11. Estimated completion is 2028-12-13.
What conditions does trial NCT06572384 study?
This clinical trial studies the following conditions: Lung Diseases, Interstitial. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT06572384?
The interventions under investigation include: Placebo (OTHER), Belimumab (BIOLOGICAL). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT06572384?
This trial is sponsored by GlaxoSmithKline, which has 558 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT06572384 being conducted?
This trial has 20 study locations across California, Florida, Missouri, New York, North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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