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NCT06448481 · ClinicalTrials.gov registry record · NA
Aesthetic Outcome of Intra-dermal Versus Transcutaneous Purse-string Closure
A NA study of Scarring, sponsored by University of California, Davis.
- Recruiting
- Registry status
- NA
- Development phase
- 73
- Enrollment target
- 1
- Study location
NCT06448481: Recruiting NA study of Scarring, sponsored by University of California, Davis.
NCT06448481 is a NA study of Scarring that is actively recruiting participants, run by University of California, Davis. The registered enrollment target is 73 participants, roughly in line with the 74-participant average among 8 other Scarring trials with a reported enrollment target. The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06448481, a NA study of Scarring, is actively recruiting participants, sponsored by University of California, Davis.
- RECRUITING
- Registry status
- NA
- Development phase
- 73 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to determine whether intra-dermal versus transcutaneous purse-string closures have similar scar cosmesis and post-operative complications. The investigators will use a split wound model, where half of the wound will be closed with intra-dermal purse-string sutures and the other half will be closed with a transcutaneous purse-string sutures. Three-months post-surgery, the scar will be evaluated via the patient observer scar assessment scale (POSAS), a validated scar instrument, as well as the trace-to-tape method, an objective outcome measure for linear postoperative scars. Any adverse events will also be recorded.
Primary Outcome
The primary endpoint will be the score of two blinded reviewers independently using the POSAS assessment. The observer scale of the POSAS consists of six items (vascularity, pigmentation, thickness, relief, pliability, and surface area). All items are scored on a scale ranging from 1 ("like normal skin") to 10 ("worst scar imaginable"). The sum of the six items results in a total score of the POSAS observer scale. Furthermore, an overall opinion is scored on a scale ranging from 1 to 10. All par
Conditions Studied
Interventions
- PROCEDURE Intra-dermal purse-string closure
- PROCEDURE Transcutaneous purse-string closure
Study Locations (1)
California
- University of California, Davis - Dermatology Department - Sacramento
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 73 participants |
| Start Date | 2025-10-14 |
| Est. Completion | 2027-01-01 |
| Phase | NA |
What NCT06448481 shows while recruiting
NCT06448481 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 73 participants, a relatively small participant target, roughly in line with the 74-participant average among 8 other Scarring trials with a reported enrollment target.
The record links to 1 condition, with Scarring appearing as the primary indexed condition, and to 2 interventions - of which Intra-dermal purse-string closure is the first listed.
NCT06448481 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT06448481 about?
NCT06448481 is a clinical study titled "Aesthetic Outcome of Intra-dermal Versus Transcutaneous Purse-string Closure". The purpose of this study is to determine whether intra-dermal versus transcutaneous purse-string closures have similar scar cosmesis and post-operative complications. The investigators will use a split wound model, where half of the wound will be closed with intra-dermal purse-string sutures and th...
What is the current status of trial NCT06448481?
This trial is currently recruiting. It is a NA study. The enrollment target is 73 participants. The study started on 2025-10-14. Estimated completion is 2027-01-01.
What conditions does trial NCT06448481 study?
This clinical trial studies the following conditions: Scarring.
What interventions are being tested in trial NCT06448481?
The interventions under investigation include: Intra-dermal purse-string closure (PROCEDURE), Transcutaneous purse-string closure (PROCEDURE).
Who is sponsoring clinical trial NCT06448481?
This trial is sponsored by University of California, Davis, which has 657 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06448481 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Scarring
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06448481's enrollment target sits among peer trials
73 3rd of 8 higher than 6 of 8 other Scarring trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Scarring trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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