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NCT06446453 · ClinicalTrials.gov registry record · NA
Echography-guided Surfactant THERapy (ESTHER) For Preterm Infants With Respiratory Failure
A NA study of Respiratory Distress Syndrome, Newborn and Intensive Care Units, Neonatal, sponsored by Connecticut Children's Medical Center.
- Recruiting
- Registry status
- NA
- Development phase
- 52
- Enrollment target
- 1
- Study location
NCT06446453 is a NA study of Respiratory Distress Syndrome, Newborn and Intensive Care Units, Neonatal that is actively recruiting participants, run by Connecticut Children's Medical Center. The registered enrollment target is 52 participants, below the 201-participant average among 8 other Respiratory Distress Syndrome, Newborn trials with a reported enrollment target (74% lower). The trial reports 1 study location across 1 state.
The verdict
NCT06446453, a NA study of Respiratory Distress Syndrome, Newborn and Intensive Care Units, Neonatal, is actively recruiting participants, sponsored by Connecticut Children's Medical Center.
- RECRUITING
- Registry status
- NA
- Development phase
- 52 participants
- Enrollment target
- 1
- Study location
Study Summary
Point-of-care ultrasound (POCUS) is the use of ultrasound by the bedside provider in real time to answer a specific question and guide medical management. POCUS can be used to diagnose the severity of neonatal respiratory distress syndrome (RDS) through a lung ultrasound score. Lung ultrasound scores have also been shown to predict if an infant is treated with an initial dose of surfactant. Therefore, using lung ultrasound scores to guide surfactant therapy for RDS will likely lead to earlier surfactant therapy and may improve short-term respiratory outcomes. This study will test this theory by comparing lung ultrasound score-guided surfactant therapy for premature infants with RDS with our current surfactant administration guidelines.
Conditions Studied
Interventions
- DIAGNOSTIC_TEST Echography-guided Surfactant THERapy (ESTHER)
Study Locations (1)
Connecticut
- Connecticut Children's - Hartford
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 52 participants |
| Start Date | 2024-06-25 |
| Est. Completion | 2026-06 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06446453
The ClinicalTrials.gov registry entry for NCT06446453 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 52 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 201-participant average among 8 other Respiratory Distress Syndrome, Newborn trials with a reported enrollment target (74% lower). The listed sponsor is Connecticut Children's Medical Center, which has 55 total studies on file at ClinicalTrials.gov.
The record links to 3 conditions, with Respiratory Distress Syndrome, Newborn appearing as the primary indexed condition, and to 1 intervention - of which Echography-guided Surfactant THERapy (ESTHER) is the first listed.
NCT06446453 reports 1 study location spanning 1 distinct geographic area - top geographies include Connecticut.
Frequently Asked Questions
What is clinical trial NCT06446453 about?
NCT06446453 is a clinical study titled "Echography-guided Surfactant THERapy (ESTHER) For Preterm Infants With Respiratory Failure". Point-of-care ultrasound (POCUS) is the use of ultrasound by the bedside provider in real time to answer a specific question and guide medical management. POCUS can be used to diagnose the severity of neonatal respiratory distress syndrome (RDS) through a lung ultrasound score. Lung ultrasound score...
What is the current status of trial NCT06446453?
This trial is currently recruiting. It is a NA study. The enrollment target is 52 participants. The study started on 2024-06-25. Estimated completion is 2026-06.
What conditions does trial NCT06446453 study?
This clinical trial studies the following conditions: Respiratory Distress Syndrome, Newborn, Intensive Care Units, Neonatal, Pulmonary Surfactants.
What interventions are being tested in trial NCT06446453?
The interventions under investigation include: Echography-guided Surfactant THERapy (ESTHER) (DIAGNOSTIC_TEST).
Who is sponsoring clinical trial NCT06446453?
This trial is sponsored by Connecticut Children's Medical Center, which has 55 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06446453 being conducted?
This trial has 1 study location across Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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