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NCT06378736 · ClinicalTrials.gov registry record
Electroencephalogram Recording in Patients With Systemic Lupus Erythematosus
A clinical trial of Systemic Lupus Erythematosus, sponsored by Northwell Health.
- Recruiting
- Registry status
- 40
- Enrollment target
- 1
- Study location
NCT06378736: Recruiting study of Systemic Lupus Erythematosus, sponsored by Northwell Health.
NCT06378736 is a study of Systemic Lupus Erythematosus that is actively recruiting participants, run by Northwell Health. The registered enrollment target is 40 participants, below the 380-participant average among 99 other Systemic Lupus Erythematosus trials with a reported enrollment target (89% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06378736, a study of Systemic Lupus Erythematosus, is actively recruiting participants, sponsored by Northwell Health.
- RECRUITING
- Registry status
- 40 participants
- Enrollment target
- 1
- Study location
Study Summary
Patients with systemic lupus erythematosus (SLE) often experience a frustrating decline of their cognitive skills that includes considerable problems in attention, learning, and memory. This lupus-related cognitive dysfunction (termed SLE-CD) is recognized as the most prevalent of the nineteen neuropsychiatric SLE syndromes, as it affects up to 80% of patients and can significantly decrease their quality of life. The goal is to have tools that can be used for diagnosis and for monitoring responses after targeted interventions and therapies. This study will focus on electroencephalographic (EEG) signals, which will be detected noninvasively from scalp placed surface electrodes while the subjects are in a state of wakeful rest. Our hypothesis is that a subset of brain oscillations known as theta and gamma, and their co-modulation or coupling will be disrupted in SLE patients. This research protocol will subject patients with systemic lupus erythematosus (SLE) to scalp electroencephalography (EEG), with the goal of determining whether specific EEG patterns ('theta-gamma coupling') appear abnormal during wakeful-rest periods of 20 minutes. The investigators are interested in using scalp EEG because it is a standard, safe and robust technique for monitoring the electrophysiological activity of neurons in the cerebral cortex.
Conditions Studied
Interventions
- OTHER Electroencephalography (EEG) signals, which will be detected noninvasively from dry scalp surface electrodes while the subjects are in a state of wakeful rest.
Study Locations (1)
New York
- Northwell Health-Feinstein Insitute - Manhasset
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2024-01-22 |
| Est. Completion | 2026-03-23 |
What NCT06378736 shows while recruiting
NCT06378736 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 380-participant average among 99 other Systemic Lupus Erythematosus trials with a reported enrollment target (89% lower).
The record links to 1 condition, with Systemic Lupus Erythematosus appearing as the primary indexed condition, and to 1 intervention - of which Electroencephalography (EEG) signals, which will be detected noninvasively from dry scalp surface electrodes while the subjects are in a state of wakeful rest. is the first listed.
NCT06378736 reports a single indexed study location in New York.
Frequently Asked Questions
What is clinical trial NCT06378736 about?
NCT06378736 is a clinical study titled "Electroencephalogram Recording in Patients With Systemic Lupus Erythematosus". Patients with systemic lupus erythematosus (SLE) often experience a frustrating decline of their cognitive skills that includes considerable problems in attention, learning, and memory. This lupus-related cognitive dysfunction (termed SLE-CD) is recognized as the most prevalent of the nineteen neuro...
What is the current status of trial NCT06378736?
This trial is currently recruiting. The enrollment target is 40 participants. The study started on 2024-01-22. Estimated completion is 2026-03-23.
What conditions does trial NCT06378736 study?
This clinical trial studies the following conditions: Systemic Lupus Erythematosus.
What interventions are being tested in trial NCT06378736?
The interventions under investigation include: Electroencephalography (EEG) signals, which will be detected noninvasively from dry scalp surface electrodes while the subjects are in a state of wakeful rest. (OTHER).
Who is sponsoring clinical trial NCT06378736?
This trial is sponsored by Northwell Health, which has 370 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06378736 being conducted?
This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT06378736's enrollment target sits among peer trials
40 75th of 99 higher than 22 of 99 other Systemic Lupus Erythematosus trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Systemic Lupus Erythematosus trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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