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RECRUITING

Long-Term Follow-up Study for Subjects With CHB Previously Treated With Imdusiran (AB729)

NCT06277037 · View on ClinicalTrials.gov ↗

Study Summary

This is a long term follow-up study for chronic hepatitis B (CHB) subjects who have received imdusiran treatment in a prior clinical trial, stopped NA therapy during that trial, and remain off therapy. Subjects may enroll after completing the end of study visit (baseline visit within 12 weeks ± 1 week from the end of study \[EOS\] visit) from their imdusiran clinical trial (the "parent study"). No interventions will be performed in this study other than blood sample collections, review of current medications, and reporting of any adverse events related to study procedures or NA therapy if restarted. Study participation will be for approximately 2 years (to complete a total of at least 3 years of follow-up while off NA therapy, inclusive of parent study participation).

Conditions Studied

Interventions

  • OTHER Non-interventional

Study Locations (18)

Other

  • Fiona Stanley Hospital — Murdoch
  • Queen Mary Hospital — Hong Kong
  • Arensia Exploratory Medicine Moldova — Chisinau
  • Asan Medial Center — Seoul
  • Changhua Christian Hospital — Changhua
  • Chia-Yi Christian Hospital — Chiayi City
  • Kaohsiung Medical University Chung-Ho Memorial Hospital — Kaohsiung City
  • E-Da Hospital — Kaohsiung City
  • Taichung Veterans General Hospital — Taichung
  • Chang Gung Medical Foundation Linkou — Taoyuan District
  • University Hospital of Wales, Cardiff — Cardiff
  • Royal London Hospital — London
  • King's College Hospital — London

California

  • Research and Education Inc. — San Diego

Florida

  • University of Miami Miller School of Medicine — Miami

New Jersey

  • Infectious Disease Care — Hillsborough

Victoria

  • The Alfred Hospital — Melbourne

New Territories

  • Prince of Wales Hospital — Shatin

Trial Details

FieldValue
Enrollment Target 50 participants
Start Date 2024-07-11
Est. Completion 2029-10-30

Sponsor

Arbutus Biopharma Corporation

2 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT06277037

The ClinicalTrials.gov registry entry for NCT06277037 describes a study currently listed as recruiting. It is categorized as an unspecified phase, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 50 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Arbutus Biopharma Corporation, which has 2 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Long Term Follow-up appearing as the primary indexed condition, and to 1 intervention — of which Non-interventional is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT06277037 reports 18 study locations spanning 6 distinct geographic areas — top geographies include Other, California, Florida. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT06277037 about?

NCT06277037 is a clinical study titled "Long-Term Follow-up Study for Subjects With CHB Previously Treated With Imdusiran (AB729)". This is a long term follow-up study for chronic hepatitis B (CHB) subjects who have received imdusiran treatment in a prior clinical trial, stopped NA therapy during that trial, and remain off therapy. Subjects may enroll after completing the end of study visit (baseline visit within 12 weeks ± 1 we...

What is the current status of trial NCT06277037?

This trial is currently recruiting. The enrollment target is 50 participants. The study started on 2024-07-11. Estimated completion is 2029-10-30.

What conditions does trial NCT06277037 study?

This clinical trial studies the following conditions: Long Term Follow-up. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT06277037?

The interventions under investigation include: Non-interventional (OTHER). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT06277037?

This trial is sponsored by Arbutus Biopharma Corporation, which has 2 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT06277037 being conducted?

This trial has 18 study locations across California, Florida, New Jersey, Victoria, New Territories. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial