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NCT06252519 · ClinicalTrials.gov registry record · NA

Pharmacokinetic Profile of N-Acetyl Cysteine

A NA study of Pharmacokinetics, sponsored by University of Memphis.

Completed
Registry status
NA
Development phase
8
Enrollment target
1
Study location

NCT06252519 is a NA study of Pharmacokinetics that has completed, run by University of Memphis. The registered enrollment target is 8 participants, below the 62-participant average among 37 other Pharmacokinetics trials with a reported enrollment target (87% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT06252519, a NA study of Pharmacokinetics, has completed, sponsored by University of Memphis.

COMPLETED
Registry status
NA
Development phase
8 participants
Enrollment target
1
Study location

Study Summary

The study compares three different formulations containing N-Acetyl Cysteine, with regards to acute absorption over a 24-hour period, following single ingestion. The formulations are traditional N-Acetyl Cysteine, N-Acetyl Cysteine Ethyl Ester, and a product containing a combination of N-Acetyl Cysteine Ethyl Ester, glycine, and two minerals with antioxidant potential (selenium and molybdenum) that might enhance the effect of N-Acetyl Cysteine Ethyl Ester. Subjects will report to the lab on three different occasions to consume the products, using a randomized cross-over design, and blood will be collected periodically (for the initial 8 hours and then again at 24 hours) per standard, routinely used pharmacokinetic /pharmacodynamic study protocols for evaluation of circulating glutathione concentrations. The hypothesis for this study is that the combination of N-Acetyl Cysteine Ethyl Ester + glycine will yield the greatest increase in glutathione, followed by N-Acetyl Cysteine Ethyl Ester, followed by N-Acetyl Cysteine. These findings will provide initial evidence specific to the bioavailability of these treatments following a single acute ingestion and may guide future recommendations regarding routine use.

Conditions Studied

Interventions

  • DIETARY_SUPPLEMENT NAC
  • DIETARY_SUPPLEMENT Neuro-NAC
  • DIETARY_SUPPLEMENT Neuro-NAC XS

Study Locations (1)

Tennessee

  • Center for Nutraceutical and Dietary Supplement Research - Memphis

Trial Details

FieldValue
Enrollment Target 8 participants
Start Date 2023-09-18
Est. Completion 2024-05-22
Phase NA

Sponsor

University of Memphis

35 total trials

What the Registry Record Tells You About NCT06252519

The ClinicalTrials.gov registry entry for NCT06252519 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 8 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 62-participant average among 37 other Pharmacokinetics trials with a reported enrollment target (87% lower). The listed sponsor is University of Memphis, which has 35 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Pharmacokinetics appearing as the primary indexed condition, and to 3 interventions - of which NAC is the first listed.

NCT06252519 reports 1 study location spanning 1 distinct geographic area - top geographies include Tennessee.

Frequently Asked Questions

What is clinical trial NCT06252519 about?

NCT06252519 is a clinical study titled "Pharmacokinetic Profile of N-Acetyl Cysteine". The study compares three different formulations containing N-Acetyl Cysteine, with regards to acute absorption over a 24-hour period, following single ingestion. The formulations are traditional N-Acetyl Cysteine, N-Acetyl Cysteine Ethyl Ester, and a product containing a combination of N-Acetyl Cyst...

What is the current status of trial NCT06252519?

This trial is currently completed. It is a NA study. The enrollment target is 8 participants. The study started on 2023-09-18. Estimated completion is 2024-05-22.

What conditions does trial NCT06252519 study?

This clinical trial studies the following conditions: Pharmacokinetics.

What interventions are being tested in trial NCT06252519?

The interventions under investigation include: NAC (DIETARY_SUPPLEMENT), Neuro-NAC (DIETARY_SUPPLEMENT), Neuro-NAC XS (DIETARY_SUPPLEMENT).

Who is sponsoring clinical trial NCT06252519?

This trial is sponsored by University of Memphis, which has 35 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06252519 being conducted?

This trial has 1 study location across Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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