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NCT06237868 · ClinicalTrials.gov registry record · NA
rTMS Over the Dorsolateral Prefrontal Cortex for the Treatment of Impulse Control Disorders in Parkinson's Disease
A NA study of Parkinson Disease and Impulse Control Disorder, sponsored by West Virginia University.
- Recruiting
- Registry status
- NA
- Development phase
- 20
- Enrollment target
- 1
- Study location
NCT06237868: Recruiting NA study of Parkinson Disease and Impulse Control Disorder, sponsored by West Virginia University.
NCT06237868 is a NA study of Parkinson Disease and Impulse Control Disorder that is actively recruiting participants, run by West Virginia University. The registered enrollment target is 20 participants, below the 5,326-participant average among 297 other Parkinson Disease trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06237868, a NA study of Parkinson Disease and Impulse Control Disorder, is actively recruiting participants, sponsored by West Virginia University.
- RECRUITING
- Registry status
- NA
- Development phase
- 20 participants
- Enrollment target
- 1
- Study location
Study Summary
This study's objective is to evaluate the effects of repetitive transcranial magnetic stimulation (rTMS) over the dorsolateral prefrontal cortex (dlPFC) of patients with Parkinson's Disease (PD) who experience impulse control disorders (ICDs) on impulse control symptoms and cognitive behaviors linked to ICDs: reinforcement learning and delay-discounting. This is a randomized sham-controlled cross-over trial. All patients will undergo a session of active rTMS and a session of sham rTMS, with the order of sessions randomized across participants. Following recruitment and eligibility screening, the eligible participants will undergo two sessions of rTMS (active and sham), immediately followed by neurocognitive tasks and questionnaires, no more than 1-2 weeks apart. Each session will have a duration of approximately 1-1.5 hours.
Primary Outcome
Change in performance on a task assessing delay-discounting. Delay-discounting assesses the participants' impulsivity by requiring them to make choices between smaller sooner hypothetical money rewards and larger later hypothetical money rewards (e.g. $10 today vs $100 in a year). This is a hypothetical choice, and the participant will not be receiving the chosen rewards. A short preliminary version of the task will be completed at the start of the first session (prior to TMS) to optimize task p
Conditions Studied
Interventions
- DEVICE rTMS Active
- DEVICE rTMS Sham
Study Locations (1)
West Virginia
- West Virginia University Hospitals - Morgantown
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2024-05-01 |
| Est. Completion | 2026-05 |
| Phase | NA |
What NCT06237868 shows while recruiting
NCT06237868 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 5,326-participant average among 297 other Parkinson Disease trials with a reported enrollment target (100% lower).
The record links to 2 conditions, with Parkinson Disease appearing as the primary indexed condition, and to 2 interventions - of which rTMS Active is the first listed.
NCT06237868 reports a single indexed study location in West Virginia.
Frequently Asked Questions
What is clinical trial NCT06237868 about?
NCT06237868 is a clinical study titled "rTMS Over the Dorsolateral Prefrontal Cortex for the Treatment of Impulse Control Disorders in Parkinson's Disease". This study's objective is to evaluate the effects of repetitive transcranial magnetic stimulation (rTMS) over the dorsolateral prefrontal cortex (dlPFC) of patients with Parkinson's Disease (PD) who experience impulse control disorders (ICDs) on impulse control symptoms and cognitive behaviors linke...
What is the current status of trial NCT06237868?
This trial is currently recruiting. It is a NA study. The enrollment target is 20 participants. The study started on 2024-05-01. Estimated completion is 2026-05.
What conditions does trial NCT06237868 study?
This clinical trial studies the following conditions: Parkinson Disease, Impulse Control Disorder.
What interventions are being tested in trial NCT06237868?
The interventions under investigation include: rTMS Active (DEVICE), rTMS Sham (DEVICE).
Who is sponsoring clinical trial NCT06237868?
This trial is sponsored by West Virginia University, which has 122 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06237868 being conducted?
This trial has 1 study location across West Virginia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06237868's enrollment target sits among peer trials
20 241st of 297 higher than 46 of 297 other Parkinson Disease trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Parkinson Disease trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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