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NCT06233318 · ClinicalTrials.gov registry record · NA
Sternotomy PIFB Block in Open Heart Surgery
A NA study of Autonomic Nerve Block, sponsored by Ohio State University.
- Recruiting
- Registry status
- NA
- Development phase
- 84
- Enrollment target
- 1
- Study location
NCT06233318: Recruiting NA study of Autonomic Nerve Block, sponsored by Ohio State University.
NCT06233318 is a NA study of Autonomic Nerve Block that is actively recruiting participants, run by Ohio State University. The registered enrollment target is 84 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (94% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06233318, a NA study of Autonomic Nerve Block, is actively recruiting participants, sponsored by Ohio State University.
- RECRUITING
- Registry status
- NA
- Development phase
- 84 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to evaluate if the use of a bilateral nerve block with a local anesthetic (ropivacaine), as part of a standard of care pain control regimen (called multimodal analgesia \[MMA\]), has a favorable effect on our institutional MMA pain regimen. Subjects will go through the following study procedures: review of medical history and medications subjects have taken within a month prior to surgery. Subjects will be randomly assigned to one of the two study groups (1:1) to receive either, an ultrasound-guided bilateral nerve block (called "Pecto-Intercostal Fascial Block \[PIFB\]") with ropivacaine or saline 0.9 solution, in addition to our institutional MMA regimen. A baseline line pain and nausea scores will be recorded before surgery. The block will be performed right after general anesthesia induction. The details about the surgery will be collected. Pain assessments, nausea and vomiting scores will be registered at 12, 24 and 48 hours after surgery as well. Lastly, a follow up phone call will be made by the research team to conduct a pain-detect questionnaire at 30, 60 and 90 days after surgery.
Primary Outcome
To compare the effect of bilateral PIFB on perioperative opioid consumption (MME) during the first 24 hours after surgery between groups
Conditions Studied
Interventions
- PROCEDURE Pecto-intercostal Fascial Block with 20 ml of 0.35% ropivacaine
- PROCEDURE Pecto-intercostal Fascial Block with normal saline
Study Locations (1)
Ohio
- The Ohio State University Wexner Medical Center - Columbus
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 84 participants |
| Start Date | 2023-10-16 |
| Est. Completion | 2027-01-31 |
| Phase | NA |
What NCT06233318 shows while recruiting
NCT06233318 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 84 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (94% lower).
The record links to 1 condition, with Autonomic Nerve Block appearing as the primary indexed condition, and to 2 interventions - of which Pecto-intercostal Fascial Block with 20 ml of 0.35% ropivacaine is the first listed.
NCT06233318 reports a single indexed study location in Ohio.
Frequently Asked Questions
What is clinical trial NCT06233318 about?
NCT06233318 is a clinical study titled "Sternotomy PIFB Block in Open Heart Surgery". The purpose of this study is to evaluate if the use of a bilateral nerve block with a local anesthetic (ropivacaine), as part of a standard of care pain control regimen (called multimodal analgesia \[MMA\]), has a favorable effect on our institutional MMA pain regimen. Subjects will go through the f...
What is the current status of trial NCT06233318?
This trial is currently recruiting. It is a NA study. The enrollment target is 84 participants. The study started on 2023-10-16. Estimated completion is 2027-01-31.
What conditions does trial NCT06233318 study?
This clinical trial studies the following conditions: Autonomic Nerve Block.
What interventions are being tested in trial NCT06233318?
The interventions under investigation include: Pecto-intercostal Fascial Block with 20 ml of 0.35% ropivacaine (PROCEDURE), Pecto-intercostal Fascial Block with normal saline (PROCEDURE).
Who is sponsoring clinical trial NCT06233318?
This trial is sponsored by Ohio State University, which has 552 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06233318 being conducted?
This trial has 1 study location across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT06233318's enrollment target sits among peer trials
84 983rd of 2000 higher than 1,011 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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