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NCT06165536 · ClinicalTrials.gov registry record · NA
Laryngeal and Vocal Tract Strategies to Reduce Vocal Fold Contact Pressure
A NA study of Mid-membranous Vocal Fold Lesion, sponsored by University of California, Los Angeles.
- Recruiting
- Registry status
- NA
- Development phase
- 60
- Enrollment target
- 1
- Study location
NCT06165536: Recruiting NA study of Mid-membranous Vocal Fold Lesion, sponsored by University of California, Los Angeles.
NCT06165536 is a NA study of Mid-membranous Vocal Fold Lesion that is actively recruiting participants, run by University of California, Los Angeles. The registered enrollment target is 60 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06165536, a NA study of Mid-membranous Vocal Fold Lesion, is actively recruiting participants, sponsored by University of California, Los Angeles.
- RECRUITING
- Registry status
- NA
- Development phase
- 60 participants
- Enrollment target
- 1
- Study location
Study Summary
Phonotraumatic vocal hyperfunction is one of the most frequently occurring conditions to affect the voice. This voice disorder often involves vocal fold injury due to repeated, excessive contact pressure between the vocal folds when they collide during voice production. In the clinic, voice therapy attempts to modify unhealthy vocal behaviors through different techniques or exercises. While voice therapy is generally considered effective, the scientific rationale for its therapeutic benefits still remains unclear. It is generally believed that these exercises lead to adjustments in the larynx and vocal tract that reduce vocal fold contact pressure. However, this assumption has never been tested in humans or laboratory experiments. The goal of this clinical trial is to investigate the effectiveness of voice therapy in reducing vocal fold contact pressures and in eliciting the hypothesized favorable laryngeal and vocal tract configurations.
Primary Outcome
VHI-10 scores will be measured using the voice handicap index-10 questionnaire. Scores for the VHI-10 range from 0 to 40, with higher scores indicating a greater voice-related handicap.
Conditions Studied
Interventions
- BEHAVIORAL Resonant voice therapy
Study Locations (1)
California
- UCLA Rehab Center - Los Angeles
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2025-12-01 |
| Est. Completion | 2028-01-31 |
| Phase | NA |
What NCT06165536 shows while recruiting
NCT06165536 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower).
The record links to 1 condition, with Mid-membranous Vocal Fold Lesion appearing as the primary indexed condition, and to 1 intervention - of which Resonant voice therapy is the first listed.
NCT06165536 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT06165536 about?
NCT06165536 is a clinical study titled "Laryngeal and Vocal Tract Strategies to Reduce Vocal Fold Contact Pressure". Phonotraumatic vocal hyperfunction is one of the most frequently occurring conditions to affect the voice. This voice disorder often involves vocal fold injury due to repeated, excessive contact pressure between the vocal folds when they collide during voice production. In the clinic, voice therapy ...
What is the current status of trial NCT06165536?
This trial is currently recruiting. It is a NA study. The enrollment target is 60 participants. The study started on 2025-12-01. Estimated completion is 2028-01-31.
What conditions does trial NCT06165536 study?
This clinical trial studies the following conditions: Mid-membranous Vocal Fold Lesion.
What interventions are being tested in trial NCT06165536?
The interventions under investigation include: Resonant voice therapy (BEHAVIORAL).
Who is sponsoring clinical trial NCT06165536?
This trial is sponsored by University of California, Los Angeles, which has 897 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06165536 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT06165536's enrollment target sits among peer trials
60 1164th of 2000 higher than 745 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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