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NCT06138782 · ClinicalTrials.gov registry record · NA

Identifying Networks Underlying Compulsivity in Anorexia Nervosa for Targeting With Neuromodulation

A NA study of Anorexia Nervosa, sponsored by University of California, San Francisco.

Active
Registry status
NA
Development phase
20
Enrollment target
1
Study location

NCT06138782: Active NA study of Anorexia Nervosa, sponsored by University of California, San Francisco.

NCT06138782 is a NA study of Anorexia Nervosa that is active but no longer recruiting, run by University of California, San Francisco. The registered enrollment target is 20 participants, below the 950-participant average among 43 other Anorexia Nervosa trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT06138782, a NA study of Anorexia Nervosa, is active but no longer recruiting, sponsored by University of California, San Francisco.

ACTIVE NOT RECRUITING
Registry status
NA
Development phase
20 participants
Enrollment target
1
Study location

Study Summary

Transcranial Magnetic Stimulation (TMS) is approved by the Food and Drug Administration (FDA) for the treatment of refractory Major Depressive Disorder (MDD) and obsessive-compulsive disorder (OCD). Anorexia nervosa (AN) is characterized by restrictive eating leading to low weight and associated complications. There is an emerging understanding that the symptoms of OCD and AN overlap as AN can be characterized by obsessive thought patterns around food and compulsive restricting and weight loss behaviors. Both conditions are characterized by a propensity toward cognitive inflexibility and the conditions may share neural substrates that maintain maladaptive habitual behaviors and cognitive rigidity. An evidence-based repetitive transcranial magnetic stimulation (rTMS) target for OCD is the orbitofrontal cortex (OFC). The investigators intend to determine if the OFC is also a potential rTMS target for AN and to determine if there is a characteristic pattern of functional network reorganization as characterized by functional magnetic resonance imaging (fMRI) in TMS responders.

Primary Outcome

The Eating Disorder Examination Questionnaire (EDE-Q) is a 28-item self-report questionnaire designed to assess the range, frequency and severity of behaviours associated with a diagnosis of an eating disorder. It is categorised into 4 subscales (Restraint, Eating Concern, Shape Concern and Weight Concern) and an overall global score, with a higher score indicating more problematic eating difficulties.

Conditions Studied

Interventions

  • DEVICE Repetitive Transcranial Magnetic Stimulation (rTMS)

Study Locations (1)

California

  • University of California, San Francisco - San Francisco

Trial Details

FieldValue
Enrollment Target 20 participants
Start Date 2023-10-16
Est. Completion 2026-02
Phase NA

What the registry record for NCT06138782 still lists

NCT06138782 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 950-participant average among 43 other Anorexia Nervosa trials with a reported enrollment target (98% lower).

The record links to 1 condition, with Anorexia Nervosa appearing as the primary indexed condition, and to 1 intervention - of which Repetitive Transcranial Magnetic Stimulation (rTMS) is the first listed.

NCT06138782 reports a single indexed study location in California.

Frequently Asked Questions

What is clinical trial NCT06138782 about?

NCT06138782 is a clinical study titled "Identifying Networks Underlying Compulsivity in Anorexia Nervosa for Targeting With Neuromodulation". Transcranial Magnetic Stimulation (TMS) is approved by the Food and Drug Administration (FDA) for the treatment of refractory Major Depressive Disorder (MDD) and obsessive-compulsive disorder (OCD). Anorexia nervosa (AN) is characterized by restrictive eating leading to low weight and associated com...

What is the current status of trial NCT06138782?

This trial is currently active not recruiting. It is a NA study. The enrollment target is 20 participants. The study started on 2023-10-16. Estimated completion is 2026-02.

What conditions does trial NCT06138782 study?

This clinical trial studies the following conditions: Anorexia Nervosa.

What interventions are being tested in trial NCT06138782?

The interventions under investigation include: Repetitive Transcranial Magnetic Stimulation (rTMS) (DEVICE).

Who is sponsoring clinical trial NCT06138782?

This trial is sponsored by University of California, San Francisco, which has 1,713 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06138782 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Anorexia Nervosa

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT06138782's enrollment target sits among peer trials

20 35th of 43 higher than 5 of 43 other Anorexia Nervosa trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Anorexia Nervosa trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT06138782, the US trial registry maintained by the National Library of Medicine. NCT06138782 (small enrollment · single site footprint · active not recruiting) retrieved and formatted by PlainTrial, see methodology.