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NCT06105801 · ClinicalTrials.gov registry record · Phase 4

EBUS-TBNA vs Transbronchial Mediastinal Cryobiopsy for Adequacy of Next Generation Sequencing

A Phase 4 study of Lung Cancer, sponsored by Vanderbilt-Ingram Cancer Center.

Recruiting
Registry status
Phase 4
Development phase
250
Enrollment target
1
Study location

NCT06105801 is a Phase 4 study of Lung Cancer that is actively recruiting participants, run by Vanderbilt-Ingram Cancer Center. The registered enrollment target is 250 participants, below the 935-participant average among 409 other Lung Cancer trials with a reported enrollment target (73% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT06105801, a Phase 4 study of Lung Cancer, is actively recruiting participants, sponsored by Vanderbilt-Ingram Cancer Center.

RECRUITING
Registry status
Phase 4
Development phase
250 participants
Enrollment target
1
Study location

Study Summary

This is a multi-center clinical trial evaluating the effect of transbronchial mediastinal cryobiopsy for its ability to improve the likelihood of obtaining tissue sufficient for molecular analysis. Patients in outpatient clinics or pre-operative holding areas planning to undergo a bronchoscopic biopsy of a suspected malignant lesion (peripheral or mediastinal) for initial diagnosis, staging, or tissue acquisition for molecular analysis will be considered for enrollment and consented. Patients will only be enrolled if intraoperative ROSE suggests malignancy. Patients will be randomized to continue with the operator's initial EBUS-TBNA needle or switch to a cryoprobe to perform a sampling.

Conditions Studied

Interventions

  • PROCEDURE Bronchoscopy
  • PROCEDURE Endobronchial ultrasound with transbronchial needle aspiration
  • PROCEDURE Cryobiopsy

Study Locations (1)

Tennessee

  • Vanderbilt University/Ingram Cancer Center - Nashville

Trial Details

FieldValue
Enrollment Target 250 participants
Start Date 2024-09-13
Est. Completion 2028-10-31
Phase Phase 4

Sponsor

Vanderbilt-Ingram Cancer Center

189 total trials

What the Registry Record Tells You About NCT06105801

The ClinicalTrials.gov registry entry for NCT06105801 describes a study currently listed as recruiting, categorized as Phase 4. The registered enrollment target is 250 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 935-participant average among 409 other Lung Cancer trials with a reported enrollment target (73% lower). The listed sponsor is Vanderbilt-Ingram Cancer Center, which has 189 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Lung Cancer appearing as the primary indexed condition, and to 3 interventions - of which Bronchoscopy is the first listed.

NCT06105801 reports 1 study location spanning 1 distinct geographic area - top geographies include Tennessee.

Frequently Asked Questions

What is clinical trial NCT06105801 about?

NCT06105801 is a clinical study titled "EBUS-TBNA vs Transbronchial Mediastinal Cryobiopsy for Adequacy of Next Generation Sequencing". This is a multi-center clinical trial evaluating the effect of transbronchial mediastinal cryobiopsy for its ability to improve the likelihood of obtaining tissue sufficient for molecular analysis. Patients in outpatient clinics or pre-operative holding areas planning to undergo a bronchoscopic biop...

What is the current status of trial NCT06105801?

This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 250 participants. The study started on 2024-09-13. Estimated completion is 2028-10-31.

What conditions does trial NCT06105801 study?

This clinical trial studies the following conditions: Lung Cancer.

What interventions are being tested in trial NCT06105801?

The interventions under investigation include: Bronchoscopy (PROCEDURE), Endobronchial ultrasound with transbronchial needle aspiration (PROCEDURE), Cryobiopsy (PROCEDURE).

Who is sponsoring clinical trial NCT06105801?

This trial is sponsored by Vanderbilt-Ingram Cancer Center, which has 189 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06105801 being conducted?

This trial has 1 study location across Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.