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NCT06071377 · ClinicalTrials.gov registry record
Achieving Understanding of the Natural History of Sickle Cell Trait (AUNT)
A clinical trial of Sickle Cell Trait, sponsored by National Alliance for Sickle Cell Centers.
- Recruiting
- Registry status
- 1,000
- Enrollment target
- 10
- Study locations
NCT06071377: Recruiting study of Sickle Cell Trait, sponsored by National Alliance for Sickle Cell Centers.
NCT06071377 is a study of Sickle Cell Trait that is actively recruiting participants, run by National Alliance for Sickle Cell Centers. The registered enrollment target is 1,000 participants, above the 330-participant average among 5 other Sickle Cell Trait trials with a reported enrollment target (203% higher). The trial reports 10 study locations across 8 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06071377, a study of Sickle Cell Trait, is actively recruiting participants, sponsored by National Alliance for Sickle Cell Centers.
- RECRUITING
- Registry status
- 1,000 participants
- Enrollment target
- 10
- Study locations
Study Summary
The main purpose of this study is to create a longitudinal cohort of those with Sickle Cell Trait (SCT) to better understand the hematologic phenotype for those that carry HbS, assess for differences in those with varying quantities of HbS and assess for potential clinical complications of SCT.
Primary Outcome
Determine range of variability in baseline %HbS in SCT subjects and relationship of baseline %HbS to markers of hemolysis (LDH, reticulocytes, haptoglobin), coagulopathy (D-dimer), and renal disease (urine albumin/creatinine ratio)
Conditions Studied
Interventions
- OTHER Biologic Specimen Collection
Study Locations (10)
North Carolina
- University of North Carolina - Chapel Hill
- Duke University - Durham
- East Carolina University - Greenville
Alabama
- University of Alabama - Birmingham
California
- Loma Linda University Health Care - Loma Linda
Delaware
- Nemours Children's Hospital - Wilmington
Indiana
- Indiana University - Indianapolis
Michigan
- Functional Fluidics - Detroit
Ohio
- Nationwide Children's Hospital - Columbus
Texas
- UT Health Houston - Houston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1,000 participants |
| Start Date | 2023-04-01 |
| Est. Completion | 2027-02 |
What NCT06071377 shows while recruiting
NCT06071377 is an observational study that tracks outcomes without assigning an intervention. Its 1,000 participants enrollment target places it among the larger protocols in the corpus, above the 330-participant average among 5 other Sickle Cell Trait trials with a reported enrollment target (203% higher).
The record links to 1 condition, with Sickle Cell Trait appearing as the primary indexed condition, and to 1 intervention - of which Biologic Specimen Collection is the first listed.
NCT06071377 lists 10 locations in 8 states (North Carolina, Alabama, California).
Frequently Asked Questions
What is clinical trial NCT06071377 about?
NCT06071377 is a clinical study titled "Achieving Understanding of the Natural History of Sickle Cell Trait (AUNT)". The main purpose of this study is to create a longitudinal cohort of those with Sickle Cell Trait (SCT) to better understand the hematologic phenotype for those that carry HbS, assess for differences in those with varying quantities of HbS and assess for potential clinical complications of SCT.
What is the current status of trial NCT06071377?
This trial is currently recruiting. The enrollment target is 1,000 participants. The study started on 2023-04-01. Estimated completion is 2027-02.
What conditions does trial NCT06071377 study?
This clinical trial studies the following conditions: Sickle Cell Trait.
What interventions are being tested in trial NCT06071377?
The interventions under investigation include: Biologic Specimen Collection (OTHER).
Who is sponsoring clinical trial NCT06071377?
This trial is sponsored by National Alliance for Sickle Cell Centers, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06071377 being conducted?
This trial has 10 study locations across Alabama, California, Delaware, Indiana, Michigan. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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