Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT06064851 · ClinicalTrials.gov registry record · NA
Delivering Transcutaneous Auricular Neurostimulation to Reduce Heavy Menstrual Bleeding in Patients With and Without Von Willebrand Disease
A NA study of Heavy Menstrual Bleeding and Von Willebrand Disease, Type 1, sponsored by Five Liters.
- Completed
- Registry status
- NA
- Development phase
- 29
- Enrollment target
- 1
- Study location
NCT06064851: Completed NA study of Heavy Menstrual Bleeding and Von Willebrand Disease, Type 1, sponsored by Five Liters.
NCT06064851 is a NA study of Heavy Menstrual Bleeding and Von Willebrand Disease, Type 1 that has completed, run by Five Liters. The registered enrollment target is 29 participants, below the 222-participant average among 9 other Heavy Menstrual Bleeding trials with a reported enrollment target (87% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06064851, a NA study of Heavy Menstrual Bleeding and Von Willebrand Disease, Type 1, has completed, sponsored by Five Liters.
- COMPLETED
- Registry status
- NA
- Development phase
- 29 participants
- Enrollment target
- 1
- Study location
Study Summary
The objectives of this study are to determine if transcutaneous auricular neurostimulation (tAN) can modulate hemostasis, improve perceived quality of life, and improve pain during the menstrual cycle of von Willebrand Disease (VWD) patients.
Primary Outcome
Comparison of mean Pictorial Bleeding Assessment Chart (PBAC) scores during first menstruation (no stimulation) versus second menstruation (active stimulation). The PBAC is a widely accepted tool for patients with HMB to account for menstrual blood loss. Menstrual blood loss is estimated through a selection of images of tampons, pads, clots, and flooding events. Patients mark a tally next to the images that best match each of the menstruation products they used that day. This trial will utilize
Conditions Studied
Interventions
- DEVICE Volta System
Study Locations (1)
Texas
- Five Liters - Dallas
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 29 participants |
| Start Date | 2023-10-27 |
| Est. Completion | 2025-04-18 |
| Phase | NA |
What the finished NCT06064851 record still lists
NCT06064851 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 29 participants, a relatively small participant target, below the 222-participant average among 9 other Heavy Menstrual Bleeding trials with a reported enrollment target (87% lower).
The record links to 2 conditions, with Heavy Menstrual Bleeding appearing as the primary indexed condition, and to 1 intervention - of which Volta System is the first listed.
NCT06064851 reports a single indexed study location in Texas.
Frequently Asked Questions
What is clinical trial NCT06064851 about?
NCT06064851 is a clinical study titled "Delivering Transcutaneous Auricular Neurostimulation to Reduce Heavy Menstrual Bleeding in Patients With and Without Von Willebrand Disease". The objectives of this study are to determine if transcutaneous auricular neurostimulation (tAN) can modulate hemostasis, improve perceived quality of life, and improve pain during the menstrual cycle of von Willebrand Disease (VWD) patients.
What is the current status of trial NCT06064851?
This trial is currently completed. It is a NA study. The enrollment target is 29 participants. The study started on 2023-10-27. Estimated completion is 2025-04-18.
What conditions does trial NCT06064851 study?
This clinical trial studies the following conditions: Heavy Menstrual Bleeding, Von Willebrand Disease, Type 1.
What interventions are being tested in trial NCT06064851?
The interventions under investigation include: Volta System (DEVICE).
Who is sponsoring clinical trial NCT06064851?
This trial is sponsored by Five Liters, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06064851 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Heavy Menstrual Bleeding
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06064851's enrollment target sits among peer trials
29 9th of 9 higher than 1 of 9 other Heavy Menstrual Bleeding trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Heavy Menstrual Bleeding trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Juveena Hydrogel System Feasibility Study for Heavy Menstrual Bleeding (HMB)
RECRUITING · NA
-
Transcutaneous Auricular Neurostimulation as a Treatment for Women With Heavy Menstrual Bleeding: A Dose-finding Trial
COMPLETED · NA
-
Minitouch Endometrial Ablation System Treatment for Menorrhagia: An Evaluation of Safety & Effectiveness
COMPLETED · NA
-
Heavy Menstrual Bleeding Progestin Treatment in Bleeding Disorders Study
RECRUITING
-
A Registry to Gather Real World Use Data on the Cerene® Cryotherapy Device
RECRUITING
-
Efficacy and Safety Study of XP12B in Women With Menorrhagia
COMPLETED · Phase 3
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT02429557 · 29 participants · Phase 1
Hemodynamic Mechanisms of Abdominal Compression in the Treatment of Orthostatic Hypotension in Autonomic Failure
- NCT02568878 · 29 participants · Phase 3
Creatine for Depressed Male and Female Methamphetamine Users
- NCT03014401 · 29 participants · NA
The Effect of Adipose-Derived Stem Cells for Knee Osteoarthritis
- NCT03128996 · 29 participants · Phase 1
Reduced Intensity Conditioning and Familial HLA-Mismatched BMT for Non-Malignant Disorders
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI