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COMPLETED Phase 1

Phase 1b, Open-Label Study to Evaluate the Safety, Tolerability, and Pharmacodynamics of EP262 in Subjects With Chronic Inducible Urticaria

NCT06050928 · View on ClinicalTrials.gov ↗

Study Summary

This phase 1b trial will evaluate the effects of EP262 in subjects with Chronic Inducible Urticaria (CIndU), including symptomatic dermographism and cold urticaria.

Interventions

  • DRUG Oral EP262

Study Locations (15)

Other

  • Innovaderm Research Inc. — Montreal
  • Gordon Sussman Clinical Research Inc. — North York
  • Institut fur Allergieforschung Charite - Universitatsmedizin Berlin — Berlin
  • Hospital del Mar — Barcelona
  • Hospital Arnau de Vilanova — Valencia

Florida

  • Advanced Clinical Research Institute — Tampa

Idaho

  • Treasure Valley Medical Research — Boise

Kentucky

  • Allergy & Asthma Specialists, P.S.C. — Owensboro

Maryland

  • Johns Hopkins University — Baltimore

Ohio

  • Bernstein Clinical Research Center, LLC — Cincinnati

Pennsylvania

  • Allergy and Clinical Immunology Associates — Pittsburgh

South Carolina

  • National Allergy and Asthma Research, LLC. — North Charleston

Trial Details

FieldValue
Enrollment Target 33 participants
Start Date 2023-08-30
Est. Completion 2024-10-22
Phase Phase 1

Sponsor

Escient Pharmaceuticals

2 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT06050928

The ClinicalTrials.gov registry entry for NCT06050928 describes a study currently listed as completed. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 33 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Escient Pharmaceuticals, which has 2 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Chronic Inducible Urticaria appearing as the primary indexed condition, and to 1 intervention — of which Oral EP262 is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT06050928 reports 15 study locations spanning 11 distinct geographic areas — top geographies include Other, Florida, Idaho. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT06050928 about?

NCT06050928 is a clinical study titled "Phase 1b, Open-Label Study to Evaluate the Safety, Tolerability, and Pharmacodynamics of EP262 in Subjects With Chronic Inducible Urticaria". This phase 1b trial will evaluate the effects of EP262 in subjects with Chronic Inducible Urticaria (CIndU), including symptomatic dermographism and cold urticaria.

What is the current status of trial NCT06050928?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 33 participants. The study started on 2023-08-30. Estimated completion is 2024-10-22.

What conditions does trial NCT06050928 study?

This clinical trial studies the following conditions: Chronic Inducible Urticaria. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT06050928?

The interventions under investigation include: Oral EP262 (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT06050928?

This trial is sponsored by Escient Pharmaceuticals, which has 2 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT06050928 being conducted?

This trial has 15 study locations across Florida, Idaho, Kentucky, Maryland, Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial