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An Evaluation of the AeriSeal System for CONVERTing Collateral Ventilation Status in Patients With Severe Emphysema
NCT06035120 · View on ClinicalTrials.gov ↗
Study Summary
This is a prospective, open-label, multi-center, single-arm study planned to enroll 200 subjects with heterogeneous emphysema and collateral ventilation (CV) in the target lobe. Subjects will undergo instillation of AeriSeal Foam in the target lobe and subsequent assessment of CV status using Chartis Pulmonary Assessment System. Subjects with CV- status will then undergo placement of Zephyr Valve in the target lobe for bronchoscopic lung volume reduction (BLVR) and be followed for 24 months.
Conditions Studied
Interventions
- DEVICE AeriSeal System
Study Locations (20)
Pennsylvania
- Penn Medicine — Philadelphia
- Temple University — Philadelphia
- Allegheny General Hospital — Pittsburgh
- University of Pittsburgh Medical Center (UPMC) — Pittsburgh
Illinois
- Northwestern University — Chicago
- University of Chicago Medical Center — Chicago
- OSF Saint Francis Medical Center — Peoria
Massachusetts
- Beth Israel Deaconess Medical Center — Boston
- Brigham Lung Center — Boston
Australia
- Royal Adelaide Hospital — Adelaide
- Wesley Hospital — Brisbane
Arizona
- Banner University Medical Center — Phoenix
Connecticut
- Saint Francis Hospital and Medical Center (Trinity Health of New England) — Hartford
Florida
- Orlando Health — Orlando
Michigan
- Henry Ford Hospital — Detroit
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 200 participants |
| Start Date | 2024-02-22 |
| Est. Completion | 2028-03-31 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06035120
The ClinicalTrials.gov registry entry for NCT06035120 describes a study currently listed as recruiting. It is categorized as NA, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 200 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Pulmonx Corporation, which has 2 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 2 conditions, with Emphysema or COPD appearing as the primary indexed condition, and to 1 intervention — of which AeriSeal System is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT06035120 reports 20 study locations spanning 13 distinct geographic areas — top geographies include Pennsylvania, Illinois, Massachusetts. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT06035120 about?
NCT06035120 is a clinical study titled "An Evaluation of the AeriSeal System for CONVERTing Collateral Ventilation Status in Patients With Severe Emphysema". This is a prospective, open-label, multi-center, single-arm study planned to enroll 200 subjects with heterogeneous emphysema and collateral ventilation (CV) in the target lobe. Subjects will undergo instillation of AeriSeal Foam in the target lobe and subsequent assessment of CV status using Charti...
What is the current status of trial NCT06035120?
This trial is currently recruiting. It is a NA study. The enrollment target is 200 participants. The study started on 2024-02-22. Estimated completion is 2028-03-31.
What conditions does trial NCT06035120 study?
This clinical trial studies the following conditions: Emphysema or COPD, Emphysema, Pulmonary. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT06035120?
The interventions under investigation include: AeriSeal System (DEVICE). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT06035120?
This trial is sponsored by Pulmonx Corporation, which has 2 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT06035120 being conducted?
This trial has 20 study locations across Arizona, Connecticut, Florida, Illinois, Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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