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NCT05976828 · ClinicalTrials.gov registry record · Phase 1
IBRX-042 In Participants With HPV-Associated Tumors
A Phase 1 study of HPV-Related Carcinoma, sponsored by ImmunityBio.
- Active
- Registry status
- Phase 1
- Development phase
- 12
- Enrollment target
- 3
- Study locations
NCT05976828: Active Phase 1 study of HPV-Related Carcinoma, sponsored by ImmunityBio.
NCT05976828 is a Phase 1 study of HPV-Related Carcinoma that is active but no longer recruiting, run by ImmunityBio. The registered enrollment target is 12 participants, below the 154-participant average among 10 other HPV-Related Carcinoma trials with a reported enrollment target (92% lower). The trial reports 3 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05976828, a Phase 1 study of HPV-Related Carcinoma, is active but no longer recruiting, sponsored by ImmunityBio.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 1
- Development phase
- 12 participants
- Enrollment target
- 3
- Study locations
Study Summary
The goal of this clinical trial is to determine the maximum tolerated dose and to find out the side effects of a drug called IBRX-042 at different dose levels in patients with recurrent or progressive Human Papillomavirus (HPV) associated tumors. The main questions it aims to answer are: * What is the maximum tolerated dose of IBRX-042? * How well does the study drug treat cancer? * What effects the study drug may have on the human body and cancer? Participants will receive IBRX-042 at one of three dose levels every 3 weeks for a total of 3 injections. Participants will undergo tests, exams, and procedures that are part of standard of care and for study purposes. IBRX-042 will be administered by injection every 3 weeks for a total of 3 injections.
Primary Outcome
The rate of DLTs will be assessed and the MTD determined
Conditions Studied
Interventions
- DRUG IBRX-042
Study Locations (3)
Texas
- Texas Oncology Austin Central - Austin
- The University of Texas - MD Anderson Cancer Center - Houston
California
- Chan Soon-Shiong Institute for Medicine (CSSIFM) - El Segundo
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 12 participants |
| Start Date | 2024-06-14 |
| Est. Completion | 2033-08-14 |
| Phase | Phase 1 |
What the registry record for NCT05976828 still lists
NCT05976828 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 12 participants, a relatively small participant target, below the 154-participant average among 10 other HPV-Related Carcinoma trials with a reported enrollment target (92% lower).
The record links to 1 condition, with HPV-Related Carcinoma appearing as the primary indexed condition, and to 1 intervention - of which IBRX-042 is the first listed.
NCT05976828 reports a single indexed study location in Texas, California.
Frequently Asked Questions
What is clinical trial NCT05976828 about?
NCT05976828 is a clinical study titled "IBRX-042 In Participants With HPV-Associated Tumors". The goal of this clinical trial is to determine the maximum tolerated dose and to find out the side effects of a drug called IBRX-042 at different dose levels in patients with recurrent or progressive Human Papillomavirus (HPV) associated tumors. The main questions it aims to answer are: * What is ...
What is the current status of trial NCT05976828?
This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 12 participants. The study started on 2024-06-14. Estimated completion is 2033-08-14.
What conditions does trial NCT05976828 study?
This clinical trial studies the following conditions: HPV-Related Carcinoma.
What interventions are being tested in trial NCT05976828?
The interventions under investigation include: IBRX-042 (DRUG).
Who is sponsoring clinical trial NCT05976828?
This trial is sponsored by ImmunityBio, which has 46 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05976828 being conducted?
This trial has 3 study locations across California, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for HPV-Related Carcinoma
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05976828's enrollment target sits among peer trials
12 10th of 10 higher than 1 of 10 other HPV-Related Carcinoma trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other HPV-Related Carcinoma trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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