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NCT05878795 · ClinicalTrials.gov registry record · NA

Written Exposure Therapy for Suicide Prevention

A NA study of Suicide, Attempted and Suicide Threat, sponsored by Boston University.

Recruiting
Registry status
NA
Development phase
160
Enrollment target
1
Study location

NCT05878795 is a NA study of Suicide, Attempted and Suicide Threat that is actively recruiting participants, run by Boston University. The registered enrollment target is 160 participants, below the 375-participant average among 36 other Suicide, Attempted trials with a reported enrollment target (57% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT05878795, a NA study of Suicide, Attempted and Suicide Threat, is actively recruiting participants, sponsored by Boston University.

RECRUITING
Registry status
NA
Development phase
160 participants
Enrollment target
1
Study location

Study Summary

Military service members admitted to inpatient psychiatry for self-injurious thoughts and behaviors (SITBs) represent an at-risk group for continued SITBs and rehospitalizations in the post-discharge period. However, there is an absence of evidence-based interventions designed to be delivered on inpatient psychiatric units to reduce the risk of post-discharge SITBs. To address this gap, the investigator's research group developed Written Exposure Therapy for Suicide Prevention (WET-SP), a brief, scalable, suicide-specific psychotherapy based on the written disclosure paradigm. Written disclosure, in which an individual writes about a personally stressful experience and the related thoughts and feelings, yields improvements across physical and psychiatric domains. Pilot data suggest that written exposure also yields reductions in SITBs. Yet, no study has adapted the written exposure paradigm specifically to target the amelioration of distress associated with suicidal crises and examined whether implementing WET-SP reduces the risk of subsequent SITBs and suicide-related hospitalizations. The primary objective of this randomized controlled trial (RCT) is to evaluate the efficacy of WET-SP, in reducing the incidence and severity of SITBs in active duty military service members following a psychiatric hospitalization due to suicidal ideation, suicide plans, or a suicide attempt. Secondary objectives are to evaluate a potential mechanism of change (i.e., decreases in thwarted belongingness \[cf. social disconnectedness\]) and moderator of outcomes (i.e., arc of narrative \[cf. linguistical parameters of the written narratives generated during treatment\]). Participants randomized to WET-SP + TAU will receive five sessions of WET-SP delivered by the study team during their psychiatric hospitalization plus treatment-as-usual (TAU). Participants randomized to TAU will receive daily contact and patient-centered care delivered by the acute psychiatric inpatient unit provider

Interventions

  • BEHAVIORAL TAU
  • BEHAVIORAL WET-SP

Study Locations (1)

Texas

  • University of Texas Health Center San Antonio - San Antonio

Trial Details

FieldValue
Enrollment Target 160 participants
Start Date 2024-08-20
Est. Completion 2026-06
Phase NA

Sponsor

Boston University

185 total trials

What the Registry Record Tells You About NCT05878795

The ClinicalTrials.gov registry entry for NCT05878795 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 160 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 375-participant average among 36 other Suicide, Attempted trials with a reported enrollment target (57% lower). The listed sponsor is Boston University, which has 185 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Suicide, Attempted appearing as the primary indexed condition, and to 2 interventions - of which TAU is the first listed.

NCT05878795 reports 1 study location spanning 1 distinct geographic area - top geographies include Texas.

Frequently Asked Questions

What is clinical trial NCT05878795 about?

NCT05878795 is a clinical study titled "Written Exposure Therapy for Suicide Prevention". Military service members admitted to inpatient psychiatry for self-injurious thoughts and behaviors (SITBs) represent an at-risk group for continued SITBs and rehospitalizations in the post-discharge period. However, there is an absence of evidence-based interventions designed to be delivered on inp...

What is the current status of trial NCT05878795?

This trial is currently recruiting. It is a NA study. The enrollment target is 160 participants. The study started on 2024-08-20. Estimated completion is 2026-06.

What conditions does trial NCT05878795 study?

This clinical trial studies the following conditions: Suicide, Attempted, Suicide Threat.

What interventions are being tested in trial NCT05878795?

The interventions under investigation include: TAU (BEHAVIORAL), WET-SP (BEHAVIORAL).

Who is sponsoring clinical trial NCT05878795?

This trial is sponsored by Boston University, which has 185 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05878795 being conducted?

This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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