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NCT05878795 · ClinicalTrials.gov registry record · NA

Written Exposure Therapy for Suicide Prevention

A NA study of Suicide, Attempted and Suicide Threat, sponsored by Boston University.

Recruiting
Registry status
NA
Development phase
160
Enrollment target
1
Study location

NCT05878795: Recruiting NA study of Suicide, Attempted and Suicide Threat, sponsored by Boston University.

NCT05878795 is a NA study of Suicide, Attempted and Suicide Threat that is actively recruiting participants, run by Boston University. The registered enrollment target is 160 participants, below the 375-participant average among 36 other Suicide, Attempted trials with a reported enrollment target (57% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05878795, a NA study of Suicide, Attempted and Suicide Threat, is actively recruiting participants, sponsored by Boston University.

RECRUITING
Registry status
NA
Development phase
160 participants
Enrollment target
1
Study location

Study Summary

Military service members admitted to inpatient psychiatry for self-injurious thoughts and behaviors (SITBs) represent an at-risk group for continued SITBs and rehospitalizations in the post-discharge period. However, there is an absence of evidence-based interventions designed to be delivered on inpatient psychiatric units to reduce the risk of post-discharge SITBs. To address this gap, the investigator's research group developed Written Exposure Therapy for Suicide Prevention (WET-SP), a brief, scalable, suicide-specific psychotherapy based on the written disclosure paradigm. Written disclosure, in which an individual writes about a personally stressful experience and the related thoughts and feelings, yields improvements across physical and psychiatric domains. Pilot data suggest that written exposure also yields reductions in SITBs. Yet, no study has adapted the written exposure paradigm specifically to target the amelioration of distress associated with suicidal crises and examined whether implementing WET-SP reduces the risk of subsequent SITBs and suicide-related hospitalizations. The primary objective of this randomized controlled trial (RCT) is to evaluate the efficacy of WET-SP, in reducing the incidence and severity of SITBs in active duty military service members following a psychiatric hospitalization due to suicidal ideation, suicide plans, or a suicide attempt. Secondary objectives are to evaluate a potential mechanism of change (i.e., decreases in thwarted belongingness \[cf. social disconnectedness\]) and moderator of outcomes (i.e., arc of narrative \[cf. linguistical parameters of the written narratives generated during treatment\]). Participants randomized to WET-SP + TAU will receive five sessions of WET-SP delivered by the study team during their psychiatric hospitalization plus treatment-as-usual (TAU). Participants randomized to TAU will receive daily contact and patient-centered care delivered by the acute psychiatric inpatient unit provider

Primary Outcome

Measured by the Depressive Symptom Index-Suicidality Subscale (DSI-SS) which is a four-item self-report focusing on frequency and intensity of suicidal thoughts and urges during the past 2 weeks. Each item is scored on a 4-point Likert scale ranging from 0 to 3. Total scores can range from 0 to 12, with higher scores representing increased severity of suicidal ideation.

Interventions

  • BEHAVIORAL TAU
  • BEHAVIORAL WET-SP

Study Locations (1)

Texas

  • University of Texas Health Center San Antonio - San Antonio

Trial Details

FieldValue
Enrollment Target 160 participants
Start Date 2024-08-20
Est. Completion 2026-06
Phase NA
Boston University

185 total trials

What NCT05878795 shows while recruiting

NCT05878795 is an interventional study that assigns participants to a tested intervention. The registered 160 participants enrollment target is mid-sized for trials with a published cap, below the 375-participant average among 36 other Suicide, Attempted trials with a reported enrollment target (57% lower).

The record links to 2 conditions, with Suicide, Attempted appearing as the primary indexed condition, and to 2 interventions - of which TAU is the first listed.

NCT05878795 reports a single indexed study location in Texas.

Frequently Asked Questions

What is clinical trial NCT05878795 about?

NCT05878795 is a clinical study titled "Written Exposure Therapy for Suicide Prevention". Military service members admitted to inpatient psychiatry for self-injurious thoughts and behaviors (SITBs) represent an at-risk group for continued SITBs and rehospitalizations in the post-discharge period. However, there is an absence of evidence-based interventions designed to be delivered on inp...

What is the current status of trial NCT05878795?

This trial is currently recruiting. It is a NA study. The enrollment target is 160 participants. The study started on 2024-08-20. Estimated completion is 2026-06.

What conditions does trial NCT05878795 study?

This clinical trial studies the following conditions: Suicide, Attempted, Suicide Threat.

What interventions are being tested in trial NCT05878795?

The interventions under investigation include: TAU (BEHAVIORAL), WET-SP (BEHAVIORAL).

Who is sponsoring clinical trial NCT05878795?

This trial is sponsored by Boston University, which has 185 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05878795 being conducted?

This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Suicide, Attempted

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT05878795's enrollment target sits among peer trials

160 18th of 36 higher than 19 of 36 other Suicide, Attempted trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Suicide, Attempted trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT05878795, the US trial registry maintained by the National Library of Medicine. NCT05878795 (mid enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.