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A Study Evaluating the Effects of GLPG3667 Administered as Oral Treatment in Adult Participants With Active Systemic Lupus Erythematosus
NCT05856448 · View on ClinicalTrials.gov ↗
Study Summary
A study evaluating the efficacy, safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of GLPG3667 administered orally once daily for 48 weeks in approximately 180 adult participants with active Systemic Lupus Erythematosus (SLE).
Conditions Studied
Interventions
- DRUG Placebo
- DRUG GLPG3667
Study Locations (20)
Florida
- Arthritis & Rheumatic Disease Specialties — Aventura
- Omega Research DeBary — DeBary
- Alloy Clinical Research, LLC — Kissimmee
- San Marcus Research Clinic — Miami
- Advanced Pharma - Miami — Miami
- Professional Research Center — Miami
- Integral Rheumatology & Immunology Specialists — Plantation
- Alliance Clinical Research of Tampa — Tampa
California
- University of California San Diego — La Jolla
- Desert Medical Advances — Rancho Mirage
- Millennium Clinical Trials — Simi Valley
- Inland Rheumatology Clinical Trials — Upland
- Upland Rheumatology Center — Upland
Tennessee
- New Phase Research & Development — Knoxville
- Office of Ramesh C. Gupta MD / Shelby Research LLC - Tennessee — Memphis
Arizona
- University of Arizona College of Medicine - Tucson — Tucson
New Mexico
- Albuquerque Clinical Trials — Albuquerque
North Carolina
- DJL Clinical Research — Charlotte
Oklahoma
- Lynn Institute of Tulsa — Tulsa
Texas
- Care and Cure Clinic — Houston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 186 participants |
| Start Date | 2023-06-28 |
| Est. Completion | 2026-03 |
| Phase | Phase 2 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05856448
The ClinicalTrials.gov registry entry for NCT05856448 describes a study currently listed as active not recruiting. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 186 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Galapagos, which has 7 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Systemic Lupus Erythematosus appearing as the primary indexed condition, and to 2 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT05856448 reports 20 study locations spanning 8 distinct geographic areas — top geographies include Florida, California, Tennessee. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT05856448 about?
NCT05856448 is a clinical study titled "A Study Evaluating the Effects of GLPG3667 Administered as Oral Treatment in Adult Participants With Active Systemic Lupus Erythematosus". A study evaluating the efficacy, safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of GLPG3667 administered orally once daily for 48 weeks in approximately 180 adult participants with active Systemic Lupus Erythematosus (SLE).
What is the current status of trial NCT05856448?
This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 186 participants. The study started on 2023-06-28. Estimated completion is 2026-03.
What conditions does trial NCT05856448 study?
This clinical trial studies the following conditions: Systemic Lupus Erythematosus. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT05856448?
The interventions under investigation include: Placebo (DRUG), GLPG3667 (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT05856448?
This trial is sponsored by Galapagos, which has 7 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT05856448 being conducted?
This trial has 20 study locations across Arizona, California, Florida, New Mexico, North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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