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RECRUITING NA

Distal Femur Fx: ORIF(Open Reduction and Internal Fixation) vs DFR (Distal Femur Replacement Total Knee Arthroplasty)

NCT05792189 · View on ClinicalTrials.gov ↗

Study Summary

Supracondylar femur periprosthetic fractures about a total knee arthroplasty (TKA) are a catastrophic and challenging complication of TKA and unfortunately are increasing in incidence. Fixation of these fractures can be challenging due to altered anatomy for the TKA and the presence of the metallic femoral component and have a relatively high complication rate. As a result, some surgeons elect to treat these fractures with a distal femur replacement total knee arthroplasty (DFR). The purpose of this study is to prospectively evaluate periprosthetic femur fractures treated with ORIF or DFR and compare various outcomes measures (Get up and go times, KOOS Jr score)

Conditions Studied

Interventions

  • OTHER Timed Up and Go Test on subjects with ORIF of distal femur fractures
  • OTHER Koos Jr assesment on subjects with ORIF of distal femur fractures
  • OTHER Timed Up and Go Test on subjects with DFR of distal femur fracture
  • OTHER Koos Jr assesment on subjects with DFR of distal femur fracture

Study Locations (1)

Florida

  • UF & Shands Orthopaedics and Sports Medicine Institute — Gainesville

Trial Details

FieldValue
Enrollment Target 100 participants
Start Date 2023-04-12
Est. Completion 2029-04-01
Phase NA

Sponsor

University of Florida

1,066 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT05792189

The ClinicalTrials.gov registry entry for NCT05792189 describes a study currently listed as recruiting. It is categorized as NA, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 100 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Florida, which has 1,066 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Distal Femur Fracture appearing as the primary indexed condition, and to 4 interventions — of which Timed Up and Go Test on subjects with ORIF of distal femur fractures is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT05792189 reports 1 study location spanning 1 distinct geographic area — top geographies include Florida. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT05792189 about?

NCT05792189 is a clinical study titled "Distal Femur Fx: ORIF(Open Reduction and Internal Fixation) vs DFR (Distal Femur Replacement Total Knee Arthroplasty)". Supracondylar femur periprosthetic fractures about a total knee arthroplasty (TKA) are a catastrophic and challenging complication of TKA and unfortunately are increasing in incidence. Fixation of these fractures can be challenging due to altered anatomy for the TKA and the presence of the metallic ...

What is the current status of trial NCT05792189?

This trial is currently recruiting. It is a NA study. The enrollment target is 100 participants. The study started on 2023-04-12. Estimated completion is 2029-04-01.

What conditions does trial NCT05792189 study?

This clinical trial studies the following conditions: Distal Femur Fracture. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT05792189?

The interventions under investigation include: Timed Up and Go Test on subjects with ORIF of distal femur fractures (OTHER), Koos Jr assesment on subjects with ORIF of distal femur fractures (OTHER), Timed Up and Go Test on subjects with DFR of distal femur fracture (OTHER), Koos Jr assesment on subjects with DFR of distal femur fracture (OTHER). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT05792189?

This trial is sponsored by University of Florida, which has 1,066 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT05792189 being conducted?

This trial has 1 study location across Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial