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Study of VGA039 in Healthy Volunteers and Patients With Von Willebrand Disease (VIVID)
NCT05776069 · View on ClinicalTrials.gov ↗
Study Summary
The VIVID study is structured in a master protocol format comprised of multiple parts that evaluate intravenous (IV) and subcutaneous (SC) VGA039 in healthy volunteers and subjects with von Willebrand Disease (VWD) and other bleeding disorders.
Conditions Studied
Interventions
- OTHER Placebo
- DRUG VGA039
Study Locations (20)
Ontario
- Hamilton Health Sciences Corporation — Hamilton
- Queens University — Kingston
- St. Michaels Hospital — Toronto
California
- Orthopedic Institute for Children (UCLA) — Los Angeles
- UC Davis Medical Center — Sacramento
São Paulo
- Hemocentro Unicamp — Campinas
- Hospital das Clinicas - USP Endereco — São Paulo
Colorado
- University of Colorado School of Medicine — Aurora
Georgia
- Hemophilia of Georgia Center for Bleeding & Clotting Disorders of Emory — Atlanta
North Carolina
- Science 37, Inc. — Morrisville
Pennsylvania
- Hemophilia Center of Western PA — Pittsburgh
Tennessee
- Vanderbilt University Medical Center — Nashville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 116 participants |
| Start Date | 2023-03-16 |
| Est. Completion | 2029-12 |
| Phase | Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05776069
The ClinicalTrials.gov registry entry for NCT05776069 describes a study currently listed as recruiting. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 116 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Vega Therapeutics, which has 2 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Von Willebrand Diseases appearing as the primary indexed condition, and to 2 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT05776069 reports 20 study locations spanning 16 distinct geographic areas — top geographies include Ontario, California, São Paulo. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT05776069 about?
NCT05776069 is a clinical study titled "Study of VGA039 in Healthy Volunteers and Patients With Von Willebrand Disease (VIVID)". The VIVID study is structured in a master protocol format comprised of multiple parts that evaluate intravenous (IV) and subcutaneous (SC) VGA039 in healthy volunteers and subjects with von Willebrand Disease (VWD) and other bleeding disorders.
What is the current status of trial NCT05776069?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 116 participants. The study started on 2023-03-16. Estimated completion is 2029-12.
What conditions does trial NCT05776069 study?
This clinical trial studies the following conditions: Von Willebrand Diseases. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT05776069?
The interventions under investigation include: Placebo (OTHER), VGA039 (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT05776069?
This trial is sponsored by Vega Therapeutics, which has 2 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT05776069 being conducted?
This trial has 20 study locations across California, Colorado, Georgia, North Carolina, Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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