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NCT05748600 · ClinicalTrials.gov registry record · Phase 3

A Study to Assess the Effect of Dexpramipexole in Adolescents and Adults With Eosinophilic Asthma

A Phase 3 study of Asthma Attack and Eosinophilic Asthma, sponsored by Areteia Therapeutics.

Active
Registry status
Phase 3
Development phase
600
Enrollment target
20
Study locations

NCT05748600 is a Phase 3 study of Asthma Attack and Eosinophilic Asthma that is active but no longer recruiting, run by Areteia Therapeutics. The registered enrollment target is 600 participants, below the 833-participant average among 4 other Asthma Attack trials with a reported enrollment target (28% lower). The trial reports 20 study locations across 2 states.

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The verdict

NCT05748600, a Phase 3 study of Asthma Attack and Eosinophilic Asthma, is active but no longer recruiting, sponsored by Areteia Therapeutics.

ACTIVE NOT RECRUITING
Registry status
Phase 3
Development phase
600 participants
Enrollment target
20
Study locations

Study Summary

The purpose of this study is to evaluate dexpramipexole as an add-on oral therapy in participants with inadequately controlled eosinophilic asthma to evaluate improvements in lung function, asthma control, and quality of life. In addition, the study will further evaluate the safety and tolerability of dexpramipexole in participants with eosinophilic asthma.

Interventions

  • DRUG Placebo
  • DRUG Dexpramipexole Dihydrochloride

Study Locations (20)

California

  • Research Site 40001-374 - Bakersfield
  • Research Site 40001-227 - Encinitas
  • Research Site 40001-349 - Huntington Beach
  • Research Site 40001-485 - Inglewood
  • Research Site 40001-440 - La Palma
  • Research Site 40001-357 - Lancaster
  • Research Site 40001-089 - Los Angeles
  • Research Site 40001-362 - Mission Viejo
  • Research Site 40001-449 - Napa
  • Research Site 40001-062 - Newport Beach
  • Research Site 40001-043 - Newport Beach
  • Research Site 40001-380 - Redding
  • Research Site 40001-434 - San Diego
  • Research Site 40001-088 - San Jose
  • Research Site 40001-359 - Upland
  • Research Site 40001-003 - West Covina
  • Research Site 40001-419 - Westminster

Arizona

  • Research Site 40001-487 - Chandler
  • Research Site 40001-462 - Peoria
  • Research Site 40001-322 - Surprise

Trial Details

FieldValue
Enrollment Target 600 participants
Start Date 2023-01-30
Est. Completion 2025-12
Phase Phase 3

Sponsor

Areteia Therapeutics

5 total trials

What the Registry Record Tells You About NCT05748600

The ClinicalTrials.gov registry entry for NCT05748600 describes a study currently listed as active not recruiting, categorized as Phase 3. The registered enrollment target is 600 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 833-participant average among 4 other Asthma Attack trials with a reported enrollment target (28% lower). The listed sponsor is Areteia Therapeutics, which has 5 total studies on file at ClinicalTrials.gov.

The record links to 3 conditions, with Asthma Attack appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT05748600 reports 20 study locations spanning 2 distinct geographic areas - top geographies include California, Arizona.

Frequently Asked Questions

What is clinical trial NCT05748600 about?

NCT05748600 is a clinical study titled "A Study to Assess the Effect of Dexpramipexole in Adolescents and Adults With Eosinophilic Asthma". The purpose of this study is to evaluate dexpramipexole as an add-on oral therapy in participants with inadequately controlled eosinophilic asthma to evaluate improvements in lung function, asthma control, and quality of life. In addition, the study will further evaluate the safety and tolerability ...

What is the current status of trial NCT05748600?

This trial is currently active not recruiting. It is a Phase 3 study. The enrollment target is 600 participants. The study started on 2023-01-30. Estimated completion is 2025-12.

What conditions does trial NCT05748600 study?

This clinical trial studies the following conditions: Asthma Attack, Eosinophilic Asthma, Asthma; Eosinophilic.

What interventions are being tested in trial NCT05748600?

The interventions under investigation include: Placebo (DRUG), Dexpramipexole Dihydrochloride (DRUG).

Who is sponsoring clinical trial NCT05748600?

This trial is sponsored by Areteia Therapeutics, which has 5 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05748600 being conducted?

This trial has 20 study locations across Arizona, California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.