Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

ACTIVE NOT RECRUITING Phase 3

A Study to Assess the Effect of Dexpramipexole in Adolescents and Adults With Eosinophilic Asthma

NCT05748600 · View on ClinicalTrials.gov ↗

Study Summary

The purpose of this study is to evaluate dexpramipexole as an add-on oral therapy in participants with inadequately controlled eosinophilic asthma to evaluate improvements in lung function, asthma control, and quality of life. In addition, the study will further evaluate the safety and tolerability of dexpramipexole in participants with eosinophilic asthma.

Interventions

  • DRUG Placebo
  • DRUG Dexpramipexole Dihydrochloride

Study Locations (20)

California

  • Research Site 40001-374 — Bakersfield
  • Research Site 40001-227 — Encinitas
  • Research Site 40001-349 — Huntington Beach
  • Research Site 40001-485 — Inglewood
  • Research Site 40001-440 — La Palma
  • Research Site 40001-357 — Lancaster
  • Research Site 40001-089 — Los Angeles
  • Research Site 40001-362 — Mission Viejo
  • Research Site 40001-449 — Napa
  • Research Site 40001-062 — Newport Beach
  • Research Site 40001-043 — Newport Beach
  • Research Site 40001-380 — Redding
  • Research Site 40001-434 — San Diego
  • Research Site 40001-088 — San Jose
  • Research Site 40001-359 — Upland
  • Research Site 40001-003 — West Covina
  • Research Site 40001-419 — Westminster

Arizona

  • Research Site 40001-487 — Chandler
  • Research Site 40001-462 — Peoria
  • Research Site 40001-322 — Surprise

Trial Details

FieldValue
Enrollment Target 600 participants
Start Date 2023-01-30
Est. Completion 2025-12
Phase Phase 3

Sponsor

Areteia Therapeutics

2 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT05748600

The ClinicalTrials.gov registry entry for NCT05748600 describes a study currently listed as active not recruiting. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 600 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Areteia Therapeutics, which has 2 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 3 conditions, with Asthma Attack appearing as the primary indexed condition, and to 2 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT05748600 reports 20 study locations spanning 2 distinct geographic areas — top geographies include California, Arizona. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT05748600 about?

NCT05748600 is a clinical study titled "A Study to Assess the Effect of Dexpramipexole in Adolescents and Adults With Eosinophilic Asthma". The purpose of this study is to evaluate dexpramipexole as an add-on oral therapy in participants with inadequately controlled eosinophilic asthma to evaluate improvements in lung function, asthma control, and quality of life. In addition, the study will further evaluate the safety and tolerability ...

What is the current status of trial NCT05748600?

This trial is currently active not recruiting. It is a Phase 3 study. The enrollment target is 600 participants. The study started on 2023-01-30. Estimated completion is 2025-12.

What conditions does trial NCT05748600 study?

This clinical trial studies the following conditions: Asthma Attack, Eosinophilic Asthma, Asthma; Eosinophilic. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT05748600?

The interventions under investigation include: Placebo (DRUG), Dexpramipexole Dihydrochloride (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT05748600?

This trial is sponsored by Areteia Therapeutics, which has 2 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT05748600 being conducted?

This trial has 20 study locations across Arizona, California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial