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RECRUITING Phase 2

CMV Immunity Monitoring in Lung Transplant Recipients

NCT05708755 · View on ClinicalTrials.gov ↗

Study Summary

The purpose of this study is to determine the safety and feasibility of using a laboratory test to guide duration of antiviral prophylaxis with valganciclovir (medication used to prevent viral infections) after lung transplant. The laboratory test, inSIGHT™ CMV T Cell Immunity Panel, measures patients' immune response to a common viral infection known as cytomegalovirus (CMV). The goal of this study will be to safely decrease how long patients need to take valganciclovir based on the results of the CMV T Cell Immunity Panel.

Interventions

  • DEVICE Cytomegalovirus T Cell Immunity Panel (CMV-TCIP)
  • DIAGNOSTIC_TEST Donor-Derived Cell-Free DNA (dd-cfDNA) Assay
  • DRUG Valganciclovir

Study Locations (1)

New York

  • NYU Langone Health — New York

Trial Details

FieldValue
Enrollment Target 50 participants
Start Date 2024-09-13
Est. Completion 2026-09
Phase Phase 2

Sponsor

NYU Langone Health

1,204 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT05708755

The ClinicalTrials.gov registry entry for NCT05708755 describes a study currently listed as recruiting. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 50 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is NYU Langone Health, which has 1,204 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Lung Transplant; Complications appearing as the primary indexed condition, and to 3 interventions — of which Cytomegalovirus T Cell Immunity Panel (CMV-TCIP) is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT05708755 reports 1 study location spanning 1 distinct geographic area — top geographies include New York. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT05708755 about?

NCT05708755 is a clinical study titled "CMV Immunity Monitoring in Lung Transplant Recipients". The purpose of this study is to determine the safety and feasibility of using a laboratory test to guide duration of antiviral prophylaxis with valganciclovir (medication used to prevent viral infections) after lung transplant. The laboratory test, inSIGHT™ CMV T Cell Immunity Panel, measures patien...

What is the current status of trial NCT05708755?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 50 participants. The study started on 2024-09-13. Estimated completion is 2026-09.

What conditions does trial NCT05708755 study?

This clinical trial studies the following conditions: Lung Transplant; Complications. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT05708755?

The interventions under investigation include: Cytomegalovirus T Cell Immunity Panel (CMV-TCIP) (DEVICE), Donor-Derived Cell-Free DNA (dd-cfDNA) Assay (DIAGNOSTIC_TEST), Valganciclovir (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT05708755?

This trial is sponsored by NYU Langone Health, which has 1,204 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT05708755 being conducted?

This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial