Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT05663684 · ClinicalTrials.gov registry record · Phase 4
Does Topical Ophthalmic Proparacaine 0.5% Prior to Probing and Irrigation Decrease Pain?
A Phase 4 study of Epiphora and Dacryostenosis, sponsored by Louisiana State University Health Sciences Center in New Orleans.
- Recruiting
- Registry status
- Phase 4
- Development phase
- 145
- Enrollment target
- 1
- Study location
NCT05663684 is a Phase 4 study of Epiphora and Dacryostenosis that is actively recruiting participants, run by Louisiana State University Health Sciences Center in New Orleans. The registered enrollment target is 145 participants. The trial reports 1 study location across 1 state.
The verdict
NCT05663684, a Phase 4 study of Epiphora and Dacryostenosis, is actively recruiting participants, sponsored by Louisiana State University Health Sciences Center in New Orleans.
- RECRUITING
- Registry status
- Phase 4
- Development phase
- 145 participants
- Enrollment target
- 1
- Study location
Study Summary
Purpose: It is unknown whether instillation of a drop of anesthetic ophthalmic solution into the eye such as proparacaine hydrochloride 0.5% prior to probing and irrigation of the tear duct (lacrimal drainage) system improves participant comfort during the procedure. To date, there have been no formal studies evaluating the possible benefit of this pretreatment. Methods: Participants 18 years and older who present to the Louisiana State University or associated outpatient ophthalmology clinic(s) with a complaint of epiphora (excessive tearing) who necessitate bilateral lower lid probing and irrigation of the lacrimal drainage system will be enrolled in the study. One eye will be randomized to receive a drop of the anesthetic Proparacaine hydrochloride 0.5% and the other eye will receive a control drop of Balanced Salt Solution (BSS). Probing and irrigation will then be performed in the usual fashion. The participant will then be questioned via survey on a pain scale of 1-5 as to the amount of subjective pain experienced on each side during the procedure. Expected Results: Investigators expect participants will experience statistically significantly less pain in eyes that have received a drop of Proparacaine hydrochloride 0.5% prior to performance of probing and irrigation compared to the eyes which have received the control drop.
Conditions Studied
Interventions
- DRUG Proparacaine Hydrochloride ophthalmic solution, USP 0.5%
- DRUG Balanced salt solution
Study Locations (1)
Louisiana
- Louisiana State University Health Sciences Center - New Orleans
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 145 participants |
| Start Date | 2020-06-30 |
| Est. Completion | 2023-01-31 |
| Phase | Phase 4 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05663684
The ClinicalTrials.gov registry entry for NCT05663684 describes a study currently listed as recruiting, categorized as Phase 4. The registered enrollment target is 145 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Louisiana State University Health Sciences Center in New Orleans, which has 45 total studies on file at ClinicalTrials.gov.
The record links to 3 conditions, with Epiphora appearing as the primary indexed condition, and to 2 interventions - of which Proparacaine Hydrochloride ophthalmic solution, USP 0.5% is the first listed.
NCT05663684 reports 1 study location spanning 1 distinct geographic area - top geographies include Louisiana.
Frequently Asked Questions
What is clinical trial NCT05663684 about?
NCT05663684 is a clinical study titled "Does Topical Ophthalmic Proparacaine 0.5% Prior to Probing and Irrigation Decrease Pain?". Purpose: It is unknown whether instillation of a drop of anesthetic ophthalmic solution into the eye such as proparacaine hydrochloride 0.5% prior to probing and irrigation of the tear duct (lacrimal drainage) system improves participant comfort during the procedure. To date, there have been no form...
What is the current status of trial NCT05663684?
This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 145 participants. The study started on 2020-06-30. Estimated completion is 2023-01-31.
What conditions does trial NCT05663684 study?
This clinical trial studies the following conditions: Epiphora, Dacryostenosis, Dacryocystitis.
What interventions are being tested in trial NCT05663684?
The interventions under investigation include: Proparacaine Hydrochloride ophthalmic solution, USP 0.5% (DRUG), Balanced salt solution (DRUG).
Who is sponsoring clinical trial NCT05663684?
This trial is sponsored by Louisiana State University Health Sciences Center in New Orleans, which has 45 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05663684 being conducted?
This trial has 1 study location across Louisiana. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.