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NCT05608837 · ClinicalTrials.gov registry record · Phase 2

Multicenter Study on the Efficacy and Safety of OCS-01 in Subjects With Uveitis Related and Post Surgical Macular Edema

A Phase 2 study of Uveitis Related Cystoid Macular Edema and Cystoid Macular Edema, Postoperative, sponsored by Quan Dong Nguyen.

Active
Registry status
Phase 2
Development phase
28
Enrollment target
8
Study locations

NCT05608837 is a Phase 2 study of Uveitis Related Cystoid Macular Edema and Cystoid Macular Edema, Postoperative that is active but no longer recruiting, run by Quan Dong Nguyen. The registered enrollment target is 28 participants. The trial reports 8 study locations across 4 states.

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The verdict

NCT05608837, a Phase 2 study of Uveitis Related Cystoid Macular Edema and Cystoid Macular Edema, Postoperative, is active but no longer recruiting, sponsored by Quan Dong Nguyen.

ACTIVE NOT RECRUITING
Registry status
Phase 2
Development phase
28 participants
Enrollment target
8
Study locations

Study Summary

The goal of the LEOPARD clinical trial is to investigate a new kind of steroid eye drops, OCS-01. Macular edema is a condition in which there is collection of fluid (edema) in the back of the eye (Macula) and it can lead to severe loss of vision. Among other causes, macular edema can happen because of a disease of the eye called Uveitis, and also after eye surgery. Treatment of macular edema remains a challenge as the condition may persist for several months and may lead to irreversible changes in the eye and poor vision. In the LEOPARD study the investigators wish to see how safe is the study drug (OCS-01) and how well it works, in resolving the fluid collection in the eye in patients with Uveitis or in patients who have had eye surgery. Participants will undergo detailed eye exam, and record their eye and medical history to see what their disease status is and if they can be included in the study based on the study criteria. If included, they will take the study drug OCS-01 in different doses for 24 weeks. During the study period, they will have regular eye exams to ensure their safety and to assess the usefulness of the study drug.

Interventions

  • DRUG OCS-01

Study Locations (8)

California

  • Retina Vitreous Associates Medical Group - Beverly Hills
  • Retina Associates of Southern California - Huntington Beach
  • Stein Eye Institute at UCLA - Los Angeles
  • Byers Eye Institute at Stanford - Palo Alto

Texas

  • Valley Retina Institute P.A - McAllen
  • Texas Retina Associates - Plano

Massachusetts

  • Massachusetts Eye Research and Surgery Institution - Boston

Pennsylvania

  • Erie Retina Research - Erie

Trial Details

FieldValue
Enrollment Target 28 participants
Start Date 2023-05-26
Est. Completion 2026-09
Phase Phase 2

Sponsor

Quan Dong Nguyen

4 total trials

What the Registry Record Tells You About NCT05608837

The ClinicalTrials.gov registry entry for NCT05608837 describes a study currently listed as active not recruiting, categorized as Phase 2. The registered enrollment target is 28 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Quan Dong Nguyen, which has 4 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Uveitis Related Cystoid Macular Edema appearing as the primary indexed condition, and to 1 intervention - of which OCS-01 is the first listed.

NCT05608837 reports 8 study locations spanning 4 distinct geographic areas - top geographies include California, Texas, Massachusetts.

Frequently Asked Questions

What is clinical trial NCT05608837 about?

NCT05608837 is a clinical study titled "Multicenter Study on the Efficacy and Safety of OCS-01 in Subjects With Uveitis Related and Post Surgical Macular Edema". The goal of the LEOPARD clinical trial is to investigate a new kind of steroid eye drops, OCS-01. Macular edema is a condition in which there is collection of fluid (edema) in the back of the eye (Macula) and it can lead to severe loss of vision. Among other causes, macular edema can happen because...

What is the current status of trial NCT05608837?

This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 28 participants. The study started on 2023-05-26. Estimated completion is 2026-09.

What conditions does trial NCT05608837 study?

This clinical trial studies the following conditions: Uveitis Related Cystoid Macular Edema, Cystoid Macular Edema, Postoperative.

What interventions are being tested in trial NCT05608837?

The interventions under investigation include: OCS-01 (DRUG).

Who is sponsoring clinical trial NCT05608837?

This trial is sponsored by Quan Dong Nguyen, which has 4 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05608837 being conducted?

This trial has 8 study locations across California, Massachusetts, Pennsylvania, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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