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Safety, Tolerability, and Pharmacokinetics of UHE-103 Cream in Subjects With Tinea Cruris and/or Tinea Pedis
NCT05363449 · View on ClinicalTrials.gov ↗
Study Summary
This Phase 1 study has been designed to determine the safety, tolerability and pharmacokinetics (PK) of UHE 103 Cream compared to Naftin Cream, 2% under maximal use conditions for 2 weeks treatment in subjects with tinea cruris and/or tinea pedis
Conditions Studied
Interventions
- DRUG UHE-103 Cream
- DRUG Naftin (naftifine hydrochloride) Cream
Study Locations (5)
Texas
- Site #2 — Austin
- Site #3 — College Station
- Site #4 — Houston
California
- Site #1 — San Diego
- Site #5 — Thousand Oaks
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 42 participants |
| Start Date | 2022-02-17 |
| Est. Completion | 2023-11-14 |
| Phase | Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05363449
The ClinicalTrials.gov registry entry for NCT05363449 describes a study currently listed as completed. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 42 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Therapeutics, which has 5 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 2 conditions, with Tinea Pedis appearing as the primary indexed condition, and to 2 interventions — of which UHE-103 Cream is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT05363449 reports 5 study locations spanning 2 distinct geographic areas — top geographies include Texas, California. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT05363449 about?
NCT05363449 is a clinical study titled "Safety, Tolerability, and Pharmacokinetics of UHE-103 Cream in Subjects With Tinea Cruris and/or Tinea Pedis". This Phase 1 study has been designed to determine the safety, tolerability and pharmacokinetics (PK) of UHE 103 Cream compared to Naftin Cream, 2% under maximal use conditions for 2 weeks treatment in subjects with tinea cruris and/or tinea pedis
What is the current status of trial NCT05363449?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 42 participants. The study started on 2022-02-17. Estimated completion is 2023-11-14.
What conditions does trial NCT05363449 study?
This clinical trial studies the following conditions: Tinea Pedis, Tinea Cruris. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT05363449?
The interventions under investigation include: UHE-103 Cream (DRUG), Naftin (naftifine hydrochloride) Cream (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT05363449?
This trial is sponsored by Therapeutics, which has 5 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT05363449 being conducted?
This trial has 5 study locations across California, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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