Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT05339061 · ClinicalTrials.gov registry record · NA
Physician Modified Endograft For Complex Aortic Aneurysm Repair
A NA study of Thoracoabdominal Aortic Aneurysm and Juxtarenal Aortic Aneurysm, sponsored by University of California, Davis.
- Recruiting
- Registry status
- NA
- Development phase
- 40
- Enrollment target
- 1
- Study location
NCT05339061: Recruiting NA study of Thoracoabdominal Aortic Aneurysm and Juxtarenal Aortic Aneurysm, sponsored by University of California, Davis.
NCT05339061 is a NA study of Thoracoabdominal Aortic Aneurysm and Juxtarenal Aortic Aneurysm that is actively recruiting participants, run by University of California, Davis. The registered enrollment target is 40 participants, below the 197-participant average among 11 other Thoracoabdominal Aortic Aneurysm trials with a reported enrollment target (80% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05339061, a NA study of Thoracoabdominal Aortic Aneurysm and Juxtarenal Aortic Aneurysm, is actively recruiting participants, sponsored by University of California, Davis.
- RECRUITING
- Registry status
- NA
- Development phase
- 40 participants
- Enrollment target
- 1
- Study location
Study Summary
The physician modified endograft is intended for treating complex, pararenal, juxtarenal and thoracoabdominal aortic aneurysms requiring coverage of renal arteries, the superior mesenteric artery or the celiac trunk in high-risk patients who do not have an option for endovascular repair with an FDA approved endograft and have an appropriate anatomy. There will be one investigational site with a total of 40 subjects to be enrolled. Time to complete enrollment will be 24 months and the subject follow-up time will be five years from last subject enrollment. The primary safety endpoint is freedom from major adverse events (MAE) at 30 days or during hospitalization if this exceeds 30 days. The primary effectiveness endpoint is the proportion of study subjects with treatment success at one year. The subjects will be followed at one month, six months, one year, and yearly thereafter for a total period of five years. Subjects will be followed up clinically for life. Clinical exam follow up may be phone or video visit with CT scan evaluation and duplex ultrasound as needed. The proportion of treatment group subjects that achieve and maintain treatment success annually to five years will be investigated.
Primary Outcome
Major adverse events include death, bowel ischemia, myocardial infarction, paraplegia, renal failure, respiratory failure, and stroke.
Conditions Studied
Interventions
- DEVICE Endovascular Treatment of Complex abdominal or Thorocoabdominal aneurysms (TAAA).
Study Locations (1)
California
- University of California San Diego - San Diego
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2023-03-01 |
| Est. Completion | 2029-12 |
| Phase | NA |
What NCT05339061 shows while recruiting
NCT05339061 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 197-participant average among 11 other Thoracoabdominal Aortic Aneurysm trials with a reported enrollment target (80% lower).
The record links to 4 conditions, with Thoracoabdominal Aortic Aneurysm appearing as the primary indexed condition, and to 1 intervention - of which Endovascular Treatment of Complex abdominal or Thorocoabdominal aneurysms (TAAA). is the first listed.
NCT05339061 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT05339061 about?
NCT05339061 is a clinical study titled "Physician Modified Endograft For Complex Aortic Aneurysm Repair". The physician modified endograft is intended for treating complex, pararenal, juxtarenal and thoracoabdominal aortic aneurysms requiring coverage of renal arteries, the superior mesenteric artery or the celiac trunk in high-risk patients who do not have an option for endovascular repair with an FDA ...
What is the current status of trial NCT05339061?
This trial is currently recruiting. It is a NA study. The enrollment target is 40 participants. The study started on 2023-03-01. Estimated completion is 2029-12.
What conditions does trial NCT05339061 study?
This clinical trial studies the following conditions: Thoracoabdominal Aortic Aneurysm, Juxtarenal Aortic Aneurysm, Pararenal Aortic Aneurysm, Complex Abdominal Aortic Aneurysm.
What interventions are being tested in trial NCT05339061?
The interventions under investigation include: Endovascular Treatment of Complex abdominal or Thorocoabdominal aneurysms (TAAA). (DEVICE).
Who is sponsoring clinical trial NCT05339061?
This trial is sponsored by University of California, Davis, which has 657 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05339061 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Thoracoabdominal Aortic Aneurysm
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05339061's enrollment target sits among peer trials
40 9th of 11 higher than 3 of 11 other Thoracoabdominal Aortic Aneurysm trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Thoracoabdominal Aortic Aneurysm trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Evaluation of Branch Endografts in the Treatment of Aortic Aneurysms
RECRUITING · NA
-
CAAAs, TAAAs, Aortic Arch Aneurysms or Dissections With Fenestrated/Branched Stent Graft
RECRUITING · NA
-
PMEG for Repair of Pararenal and Thoracoabdominal Aortic Aneurysm
RECRUITING · NA
-
Evaluation of the Cook Custom Aortic Endograft, the Zenith t-Branch Endovascular Graft, and Surgeon-Modified Endograft in Treating Aortic Pathologies
RECRUITING · NA
-
Clinical Outcomes and Major Adverse Events in Patients Treated With Physician-Modified Fenestrated and Branched Stent Grafts
RECRUITING · NA
-
Endovascular Exclusion of Thoracoabdominal and/or Paravisceral Abdominal Aortic Aneurysm
RECRUITING · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT01306019 · 40 participants · Phase 1
Lentiviral Gene Transfer for Treatment of Children Older Than Two Years of Age With X-Linked Severe Combined Immunodeficiency (XSCID)
- NCT01608152 · 40 participants
Development of a Video Game for the Improvement of Outcomes in Stem Cell Transplant Survivors
- NCT01668082 · 40 participants · NA
An Investigation of Brain Tumor Metabolism in Patients Undergoing Surgical Resection
- NCT02015013 · 40 participants · Phase 2
Hematopoietic Stem Cell Mobilization in Idiopathic CD4 Lymphocytopenia Patients and Healthy Controls for the Study of T Cell Maturation and Trafficking in Murine Models
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI