Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT05289661 · ClinicalTrials.gov registry record · Phase 3
Descemet Endothelial Thickness Comparison Trial I
A Phase 3 study of Fuchs, sponsored by Stanford University.
- Active
- Registry status
- Phase 3
- Development phase
- 160
- Enrollment target
- 7
- Study locations
NCT05289661 is a Phase 3 study of Fuchs that is active but no longer recruiting, run by Stanford University. The registered enrollment target is 160 participants. The trial reports 7 study locations across 5 states.
The verdict
NCT05289661, a Phase 3 study of Fuchs, is active but no longer recruiting, sponsored by Stanford University.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 3
- Development phase
- 160 participants
- Enrollment target
- 7
- Study locations
Study Summary
Descemet Endothelial Thickness Comparison Trial (DETECT) I is a multi-center, outcome assessor-masked, placebo-controlled clinical trial randomizing 160 patients in a 2x2 factorial design. The purpose of this study is to determine differences in visual outcomes between two types of corneal transplant surgeries, ultrathin Descemet stripping automated endothelial keratoplasty (UT-DSAEK) and Descemet membrane endothelial keratoplasty (DMEK), and to determine the effect of rho-kinase inhibitors on endothelial cell loss.
Conditions Studied
Interventions
- DRUG Topical Ripasudil
- DRUG Topical Placebo
Study Locations (7)
California
- Stanford University - Palo Alto
- University of California Davis - Sacramento
Pennsylvania
- University of Pennsylvania - Philadelphia
- Wills Eye Hospital - Philadelphia
Florida
- University of Miami - Palm Beach Gardens
New Hampshire
- Dartmouth-Hitchcock Medical Center - Lebanon
Oregon
- Oregon Health & Science University - Portland
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 160 participants |
| Start Date | 2022-07-15 |
| Est. Completion | 2027-11-30 |
| Phase | Phase 3 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05289661
The ClinicalTrials.gov registry entry for NCT05289661 describes a study currently listed as active not recruiting, categorized as Phase 3. The registered enrollment target is 160 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Stanford University, which has 1,744 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Fuchs appearing as the primary indexed condition, and to 2 interventions - of which Topical Ripasudil is the first listed.
NCT05289661 reports 7 study locations spanning 5 distinct geographic areas - top geographies include California, Pennsylvania, Florida.
Frequently Asked Questions
What is clinical trial NCT05289661 about?
NCT05289661 is a clinical study titled "Descemet Endothelial Thickness Comparison Trial I". Descemet Endothelial Thickness Comparison Trial (DETECT) I is a multi-center, outcome assessor-masked, placebo-controlled clinical trial randomizing 160 patients in a 2x2 factorial design. The purpose of this study is to determine differences in visual outcomes between two types of corneal transplan...
What is the current status of trial NCT05289661?
This trial is currently active not recruiting. It is a Phase 3 study. The enrollment target is 160 participants. The study started on 2022-07-15. Estimated completion is 2027-11-30.
What conditions does trial NCT05289661 study?
This clinical trial studies the following conditions: Fuchs.
What interventions are being tested in trial NCT05289661?
The interventions under investigation include: Topical Ripasudil (DRUG), Topical Placebo (DRUG).
Who is sponsoring clinical trial NCT05289661?
This trial is sponsored by Stanford University, which has 1,744 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05289661 being conducted?
This trial has 7 study locations across California, Florida, New Hampshire, Oregon, Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Fuchs
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.