Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT05267340 · ClinicalTrials.gov registry record · NA
Neural Mechanisms of Meditation Training in Healthy and Depressed Adolescents: An MRI Connectome Study PART 2
A NA study of Depression Mild and Depression Moderate, sponsored by University of California, San Francisco.
- Active
- Registry status
- NA
- Development phase
- 120
- Enrollment target
- 1
- Study location
NCT05267340: Active NA study of Depression Mild and Depression Moderate, sponsored by University of California, San Francisco.
NCT05267340 is a NA study of Depression Mild and Depression Moderate that is active but no longer recruiting, run by University of California, San Francisco. The registered enrollment target is 120 participants, below the 423-participant average among 7 other Depression Mild trials with a reported enrollment target (72% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05267340, a NA study of Depression Mild and Depression Moderate, is active but no longer recruiting, sponsored by University of California, San Francisco.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 120 participants
- Enrollment target
- 1
- Study location
Study Summary
The primary objective will be to study changes in putamen connectivity and depression severity in depressed teens with meditation training. H1: Putamen node strength will increase in the training group compared to the active controls. H2: This increase in node strength will correlate with practice amount recorded by participants. H3: There will be a significant reduction in self-rated depression symptoms following the training as measured by the Reynolds Adolescent Depression Scale (RADS-2), compared to controls. H4: This reduction will correlate with the increase in putamen node strength. Design and Outcomes: The current research study design will utilize an individually randomized group treatment, open-label, active-controlled clinical trial to test the efficacy and safety of the investigator's innovative mindfulness meditation intervention (Training for Awareness Resilience and Action \[TARA\]) on the primary outcome (Putamen structural node strength) and secondary outcome (depression symptoms measured using Reynolds Adolescent Depression Scale \[RADS-2\]) in depressed adolescents between the ages of 14 to 18 years old.
Primary Outcome
Change in the Putamen node strength assessed using diffusion MRI
Conditions Studied
Interventions
- BEHAVIORAL Psycho-Education
- BEHAVIORAL TARA
Study Locations (1)
California
- UCSF - San Francisco
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 120 participants |
| Start Date | 2023-02-08 |
| Est. Completion | 2026-08-31 |
| Phase | NA |
What the registry record for NCT05267340 still lists
NCT05267340 is an interventional study that assigns participants to a tested intervention. The registered 120 participants enrollment target is mid-sized for trials with a published cap, below the 423-participant average among 7 other Depression Mild trials with a reported enrollment target (72% lower).
The record links to 3 conditions, with Depression Mild appearing as the primary indexed condition, and to 2 interventions - of which Psycho-Education is the first listed.
NCT05267340 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT05267340 about?
NCT05267340 is a clinical study titled "Neural Mechanisms of Meditation Training in Healthy and Depressed Adolescents: An MRI Connectome Study PART 2". The primary objective will be to study changes in putamen connectivity and depression severity in depressed teens with meditation training. H1: Putamen node strength will increase in the training group compared to the active controls. H2: This increase in node strength will correlate with practice a...
What is the current status of trial NCT05267340?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 120 participants. The study started on 2023-02-08. Estimated completion is 2026-08-31.
What conditions does trial NCT05267340 study?
This clinical trial studies the following conditions: Depression Mild, Depression Moderate, Depression, Teen.
What interventions are being tested in trial NCT05267340?
The interventions under investigation include: Psycho-Education (BEHAVIORAL), TARA (BEHAVIORAL).
Who is sponsoring clinical trial NCT05267340?
This trial is sponsored by University of California, San Francisco, which has 1,713 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05267340 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Depression Mild
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
-
fMRI Neurofeedback With Matter Neuroscience App
RECRUITING · NA
-
Telehealth Behavioral Activation for Teens
RECRUITING · NA
-
Treating Major Depression With Yoga Mono-therapy
RECRUITING · NA
-
The S.M.A.R.T. Project: Stress Management and Resilience Training for Teens
COMPLETED · NA
-
Kintsugi Voice Device Pivotal Study
RECRUITING
-
Kintsugi Voice Device Pilot Study
ACTIVE NOT RECRUITING
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT01174108 · 120 participants · Phase 2
Allogeneic Hematopoietic Stem Cell Transplantation for Severe Aplastic Anemia and Other Bone Marrow Failure Syndromes Using G-CSF Mobilized CD34+ Selected Hematopoietic Precursor Cells Co-Infused With a Reduced Dose of Non-Mobilized Donor T-cells
- NCT01627301 · 120 participants · NA
Sympathetic Overactivity in Post-traumatic Stress Disorder
- NCT02025023 · 120 participants · Phase 3
Local 5-Fluorouracil Injection for the Treatment of Chalazia: A Prospective, Comparative Study
- NCT02128906 · 120 participants · Phase 2
Radiotherapy With Cisplatin vs. Docetaxel-cetuximab in HNSCC: ERCC1 Biomarker Enrichment and Interaction Design
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI