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NCT05219305 · ClinicalTrials.gov registry record · NA

Implant Stability in Autogenous Mineralized and Demineralized Dentin Grafts

A NA study of Edentulous Alveolar Ridge, sponsored by University of Oklahoma.

Active
Registry status
NA
Development phase
36
Enrollment target
1
Study location

NCT05219305 is a NA study of Edentulous Alveolar Ridge that is active but no longer recruiting, run by University of Oklahoma. The registered enrollment target is 36 participants. The trial reports 1 study location across 1 state.

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The verdict

NCT05219305, a NA study of Edentulous Alveolar Ridge, is active but no longer recruiting, sponsored by University of Oklahoma.

ACTIVE NOT RECRUITING
Registry status
NA
Development phase
36 participants
Enrollment target
1
Study location

Study Summary

The bone grafting materials currently used in dentistry are autografts, allografts, xenografts, and alloplastic grafts. Among these different types of bone graft materials, autografts are considered to have the most predictable results due to their properties of osteogenesis, osteoinduction, and osteoconduction. However, bone autografts are rarely used due to the high morbidity associated with harvesting the bone graft from the patient with a second surgical site. Because of the increased risk to the patient with autogenous bone grafts, the current standard of care is an allograft, which is a bone graft harvested from cadaver sources such as Freeze-Dried Bone Allograft (FDBA). While allografts can only possess the qualities of osteoinduction and osteoconduction, they also have dramatically less morbidity due to the lack of a second surgical site. Our null hypothesis states that: Experimental groups (mineralized, and partially demineralized dentin grafts) do not show positive changes in implant stability, survival, failure rate, probing pocket depth, and interproximal crestal bone level changes when compared to FDBA Our alternative hypothesis states that: Experimental groups (mineralized, and partially demineralized dentin grafts) show similar or better results in terms of implant stability, survival, failure rate, probing pocket depth, and interproximal crestal bone level changes when compared to FDBA.

Conditions Studied

Interventions

  • DEVICE Dental Implant Placement

Study Locations (1)

Oklahoma

  • University of Oklahoma College of Dentistry Graduate Periodontics - Oklahoma City

Trial Details

FieldValue
Enrollment Target 36 participants
Start Date 2022-04-01
Est. Completion 2024-12
Phase NA

Sponsor

University of Oklahoma

358 total trials

What the Registry Record Tells You About NCT05219305

The ClinicalTrials.gov registry entry for NCT05219305 describes a study currently listed as active not recruiting, categorized as NA. The registered enrollment target is 36 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Oklahoma, which has 358 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Edentulous Alveolar Ridge appearing as the primary indexed condition, and to 1 intervention - of which Dental Implant Placement is the first listed.

NCT05219305 reports 1 study location spanning 1 distinct geographic area - top geographies include Oklahoma.

Frequently Asked Questions

What is clinical trial NCT05219305 about?

NCT05219305 is a clinical study titled "Implant Stability in Autogenous Mineralized and Demineralized Dentin Grafts". The bone grafting materials currently used in dentistry are autografts, allografts, xenografts, and alloplastic grafts. Among these different types of bone graft materials, autografts are considered to have the most predictable results due to their properties of osteogenesis, osteoinduction, and ost...

What is the current status of trial NCT05219305?

This trial is currently active not recruiting. It is a NA study. The enrollment target is 36 participants. The study started on 2022-04-01. Estimated completion is 2024-12.

What conditions does trial NCT05219305 study?

This clinical trial studies the following conditions: Edentulous Alveolar Ridge.

What interventions are being tested in trial NCT05219305?

The interventions under investigation include: Dental Implant Placement (DEVICE).

Who is sponsoring clinical trial NCT05219305?

This trial is sponsored by University of Oklahoma, which has 358 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05219305 being conducted?

This trial has 1 study location across Oklahoma. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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