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A Phase 3 Study Evaluating the Efficacy and Safety of OCS-01 Eyedrops Compared to Vehicle for the Treatment of Ocular Inflammation and Pain Following Cataract Surgery
NCT05147233 · View on ClinicalTrials.gov ↗
Study Summary
This was a randomized, double-masked, vehicle-controlled, Phase 3 study evaluating the efficacy and safety of OCS-01 QD compared to vehicle in the treatment of inflammation and pain following cataract surgery.
Conditions Studied
Interventions
- DRUG Vehicle
- DRUG OCS-01
Study Locations (20)
California
- Oculis Site 9 — Inglewood
- Oculis Site 23 — Newport Beach
- Oculis Site 26 — Petaluma
- Oculis Site 24 — San Pedro
- Oculis Site 22 — Westminster
Arizona
- Oculis Site 16 — Chandler
- Oculis Site 28 — Phoenix
Missouri
- Oculis Site 5 — St Louis
- Oculis Site 3 — Washington
Ohio
- Oculis Site 6 — Brecksville
- Oculis Site 14 — Cincinnati
Arkansas
- Oculis Site 8 — Fayetteville
Colorado
- Oculis Site 11 — Fort Collins
Florida
- Oculis Site 12 — Tamarac
Georgia
- Oculis Site 17 — Morrow
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 241 participants |
| Start Date | 2022-06-24 |
| Est. Completion | 2023-07-03 |
| Phase | Phase 3 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05147233
The ClinicalTrials.gov registry entry for NCT05147233 describes a study currently listed as completed. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 241 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Oculis, which has 3 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 2 conditions, with Inflammation Eye Pain appearing as the primary indexed condition, and to 2 interventions — of which Vehicle is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT05147233 reports 20 study locations spanning 13 distinct geographic areas — top geographies include California, Arizona, Missouri. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT05147233 about?
NCT05147233 is a clinical study titled "A Phase 3 Study Evaluating the Efficacy and Safety of OCS-01 Eyedrops Compared to Vehicle for the Treatment of Ocular Inflammation and Pain Following Cataract Surgery". This was a randomized, double-masked, vehicle-controlled, Phase 3 study evaluating the efficacy and safety of OCS-01 QD compared to vehicle in the treatment of inflammation and pain following cataract surgery.
What is the current status of trial NCT05147233?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 241 participants. The study started on 2022-06-24. Estimated completion is 2023-07-03.
What conditions does trial NCT05147233 study?
This clinical trial studies the following conditions: Inflammation Eye Pain, Postoperative Cataract. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT05147233?
The interventions under investigation include: Vehicle (DRUG), OCS-01 (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT05147233?
This trial is sponsored by Oculis, which has 3 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT05147233 being conducted?
This trial has 20 study locations across Arizona, Arkansas, California, Colorado, Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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