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NCT05095727 · ClinicalTrials.gov registry record · Phase 1
A Study of mRNA-3745 in Adult and Pediatric Participants With Glycogen Storage Disease Type 1a (GSD1a)
A Phase 1 study of Glycogen Storage Disease, sponsored by ModernaTX.
- Active
- Registry status
- Phase 1
- Development phase
- 15
- Enrollment target
- 16
- Study locations
NCT05095727: Active Phase 1 study of Glycogen Storage Disease, sponsored by ModernaTX.
NCT05095727 is a Phase 1 study of Glycogen Storage Disease that is active but no longer recruiting, run by ModernaTX. The registered enrollment target is 15 participants, below the 105-participant average among 3 other Glycogen Storage Disease trials with a reported enrollment target (86% lower). The trial reports 16 study locations across 10 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05095727, a Phase 1 study of Glycogen Storage Disease, is active but no longer recruiting, sponsored by ModernaTX.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 1
- Development phase
- 15 participants
- Enrollment target
- 16
- Study locations
Study Summary
The main goal of this trial is to evaluate the safety and tolerability of mRNA-3745 via intravenous (IV) administration in adult and pediatric participants with GSD1a.
Conditions Studied
Interventions
- DRUG mRNA-3745
Study Locations (16)
Other
- AP-HP - Hôpital Antoine Béclère - Clamart
- CHRU Tours - Hopital Clocheville - Tours
- Universitair Medisch Centrum Groningen - Groningen
- Instytut Pomnik Centrum Zdrowia Dziecka - Warsaw
- Hospital Universitario 12 de Octubre - Madrid
- Hospital Regional Universitario de Malaga - Málaga
Texas
- The University of Texas Health Science Center at Houston - Houston
- Baylor College of Medicine - Houston
Connecticut
- University of Connecticut Health Center - Farmington
Massachusetts
- Boston Children's Hospital - Boston
North Carolina
- Duke University Medical Center - Durham
Ohio
- Cincinnati Children's Hospital Medical Center - Cincinnati
Pennsylvania
- Children's Hospital of Philadelphia - Philadelphia
Utah
- University of Utah - Salt Lake City
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 15 participants |
| Start Date | 2022-06-01 |
| Est. Completion | 2026-11-30 |
| Phase | Phase 1 |
What the registry record for NCT05095727 still lists
NCT05095727 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 15 participants, a relatively small participant target, below the 105-participant average among 3 other Glycogen Storage Disease trials with a reported enrollment target (86% lower).
The record links to 1 condition, with Glycogen Storage Disease appearing as the primary indexed condition, and to 1 intervention - of which mRNA-3745 is the first listed.
NCT05095727 lists 16 locations in 10 states (Other, Texas, Connecticut).
Frequently Asked Questions
What is clinical trial NCT05095727 about?
NCT05095727 is a clinical study titled "A Study of mRNA-3745 in Adult and Pediatric Participants With Glycogen Storage Disease Type 1a (GSD1a)". The main goal of this trial is to evaluate the safety and tolerability of mRNA-3745 via intravenous (IV) administration in adult and pediatric participants with GSD1a.
What is the current status of trial NCT05095727?
This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 15 participants. The study started on 2022-06-01. Estimated completion is 2026-11-30.
What conditions does trial NCT05095727 study?
This clinical trial studies the following conditions: Glycogen Storage Disease.
What interventions are being tested in trial NCT05095727?
The interventions under investigation include: mRNA-3745 (DRUG).
Who is sponsoring clinical trial NCT05095727?
This trial is sponsored by ModernaTX, which has 90 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05095727 being conducted?
This trial has 16 study locations across Connecticut, Massachusetts, North Carolina, Ohio, Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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