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NCT05090891 · ClinicalTrials.gov registry record · Phase 2

To Assess the Efficacy, Safety, and Tolerability of INCB000928 in Participants With Fibrodysplasia Ossificans Progressiva

A Phase 2 study of Fibrodysplasia Ossificans Progressiva (FOP), sponsored by Incyte Corporation.

Recruiting
Registry status
Phase 2
Development phase
98
Enrollment target
20
Study locations

NCT05090891 is a Phase 2 study of Fibrodysplasia Ossificans Progressiva (FOP) that is actively recruiting participants, run by Incyte Corporation. The registered enrollment target is 98 participants. The trial reports 20 study locations across 7 states.

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The verdict

NCT05090891, a Phase 2 study of Fibrodysplasia Ossificans Progressiva (FOP), is actively recruiting participants, sponsored by Incyte Corporation.

RECRUITING
Registry status
Phase 2
Development phase
98 participants
Enrollment target
20
Study locations

Study Summary

This Phase 2, Randomized, Double-Blind, Placebo-Controlled Study is intended to evaluate the Efficacy, Safety, and Tolerability and PK of INCB000928 administered to participants with a clinical diagnosis of fibrodysplasia ossificans progressiva (FOP).

Interventions

  • DRUG Placebo
  • DRUG INCB000928

Study Locations (20)

Other

  • Hospital Italiano de Buenos Aires - Ciudad Autonoma Buenos Aires
  • Albert Einstein Israelite Hospital - São Paulo
  • Centro de Estudios Reumatologicos - Santiago
  • Beijing Childrens Hospital Capital Medical University - Beijing
  • Tongji Hospital of Tongji University - Shanghai
  • Shanghai Childrens Medical Center - Shanghai
  • Childrens Hospital of Fudan University - Shanghai
  • Ap-Hp Hopital Lariboisiere - Paris
  • Hopital Necker-Enfants Malades - Paris
  • Uniklinik Koln - Cologne
  • Ospedale Pediatrico G. Gaslini - Genova
  • Policlinico Universitario Agostino Gemelli Universita Cattolica Del Sacro Cuore - Rome
  • Instituto Nacional de Rehabilitacion Luis Guillermo Ibarra - Tlalpan

Pennsylvania

  • Children'S Hospital of Philadelphia - Philadelphia
  • Penn Medicine - Perelman Center For Advanced Medicine - Philadelphia

California

  • University of California San Francisco Medical Center - San Francisco

Minnesota

  • Mayo Clinic Rochester - Rochester

New South Wales

  • Royal North Shore Hospital - St Leonards

Victoria

  • Murdoch Children'S Research Institute - Parkville

Ontario

  • University Health Network Toronto General Hospital - Toronto

Trial Details

FieldValue
Enrollment Target 98 participants
Start Date 2022-05-05
Est. Completion 2033-01-20
Phase Phase 2

Sponsor

Incyte Corporation

239 total trials

What the Registry Record Tells You About NCT05090891

The ClinicalTrials.gov registry entry for NCT05090891 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 98 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Incyte Corporation, which has 239 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Fibrodysplasia Ossificans Progressiva (FOP) appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT05090891 reports 20 study locations spanning 7 distinct geographic areas - top geographies include Other, Pennsylvania, California.

Frequently Asked Questions

What is clinical trial NCT05090891 about?

NCT05090891 is a clinical study titled "To Assess the Efficacy, Safety, and Tolerability of INCB000928 in Participants With Fibrodysplasia Ossificans Progressiva". This Phase 2, Randomized, Double-Blind, Placebo-Controlled Study is intended to evaluate the Efficacy, Safety, and Tolerability and PK of INCB000928 administered to participants with a clinical diagnosis of fibrodysplasia ossificans progressiva (FOP).

What is the current status of trial NCT05090891?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 98 participants. The study started on 2022-05-05. Estimated completion is 2033-01-20.

What conditions does trial NCT05090891 study?

This clinical trial studies the following conditions: Fibrodysplasia Ossificans Progressiva (FOP).

What interventions are being tested in trial NCT05090891?

The interventions under investigation include: Placebo (DRUG), INCB000928 (DRUG).

Who is sponsoring clinical trial NCT05090891?

This trial is sponsored by Incyte Corporation, which has 239 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05090891 being conducted?

This trial has 20 study locations across California, Minnesota, Pennsylvania, New South Wales, Victoria. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.