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ACTIVE NOT RECRUITING Phase 2

Study to Investigate Alternative Dosing Regimens of Belantamab Mafodotin in Participants With Relapsed or Refractory Multiple Myeloma

NCT05064358 · View on ClinicalTrials.gov ↗

Study Summary

This study aims to evaluate alternative dosing regimens of single-agent belantamab mafodotin in participants with relapsed or refractory multiple myeloma (RRMM) to determine if an improved overall benefit/risk profile can be achieved by modifying the belantamab mafodotin dose, schedule, or both.

Conditions Studied

Interventions

  • DRUG Belantamab mafodotin

Study Locations (20)

Other

  • GSK Investigational Site — Buenos Aires
  • GSK Investigational Site — Capital Federal
  • GSK Investigational Site — Ciudad Autonoma de Buenos Aire
  • GSK Investigational Site — Pilar
  • GSK Investigational Site — Rosario
  • GSK Investigational Site — Joinville
  • GSK Investigational Site — Porto Alegre
  • GSK Investigational Site — Rio de Janeiro
  • GSK Investigational Site — Salvador
  • GSK Investigational Site — São Paulo

Tennessee

  • GSK Investigational Site — Chattanooga
  • GSK Investigational Site — Nashville

New South Wales

  • GSK Investigational Site — Liverpool
  • GSK Investigational Site — Newcastle

Florida

  • GSK Investigational Site — West Palm Beach

Missouri

  • GSK Investigational Site — Kansas City

New York

  • GSK Investigational Site — New York

Texas

  • GSK Investigational Site — Houston

South Australia

  • GSK Investigational Site — Woodville

Trial Details

FieldValue
Enrollment Target 177 participants
Start Date 2022-03-03
Est. Completion 2026-01-30
Phase Phase 2

Sponsor

GlaxoSmithKline

558 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT05064358

The ClinicalTrials.gov registry entry for NCT05064358 describes a study currently listed as active not recruiting. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 177 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is GlaxoSmithKline, which has 558 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Multiple Myeloma appearing as the primary indexed condition, and to 1 intervention — of which Belantamab mafodotin is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT05064358 reports 20 study locations spanning 9 distinct geographic areas — top geographies include Other, Tennessee, New South Wales. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT05064358 about?

NCT05064358 is a clinical study titled "Study to Investigate Alternative Dosing Regimens of Belantamab Mafodotin in Participants With Relapsed or Refractory Multiple Myeloma". This study aims to evaluate alternative dosing regimens of single-agent belantamab mafodotin in participants with relapsed or refractory multiple myeloma (RRMM) to determine if an improved overall benefit/risk profile can be achieved by modifying the belantamab mafodotin dose, schedule, or both.

What is the current status of trial NCT05064358?

This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 177 participants. The study started on 2022-03-03. Estimated completion is 2026-01-30.

What conditions does trial NCT05064358 study?

This clinical trial studies the following conditions: Multiple Myeloma. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT05064358?

The interventions under investigation include: Belantamab mafodotin (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT05064358?

This trial is sponsored by GlaxoSmithKline, which has 558 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT05064358 being conducted?

This trial has 20 study locations across Florida, Missouri, New York, Tennessee, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial