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RECRUITING Phase 1

Prophylactic Antibiotics Useful With Antibiotic Impregnated External Ventricular Drains (EVDs)?

NCT05001750 · View on ClinicalTrials.gov ↗

Study Summary

The principal objective of this study is to compare the incidence of ventriculostomy related infections (VRIs) in patients who receive twenty-four hours of antibiotics, beginning no more than sixty minutes prior to EVD placement, to the incidence of VRIs in patients who also receive a pre-procedural dose of antibiotics with continued dosing of antibiotics for the duration of the external ventricular drain (EVD). At this time, the duration of prophylactic antibiotic use with antibiotic impregnated EVDs is unknown.

Interventions

  • DRUG Long term (continuous) prophylactic antibiotics
  • DRUG 24 hours antibiotics

Study Locations (1)

New York

  • Montefiore Medical Center — The Bronx

Trial Details

FieldValue
Enrollment Target 84 participants
Start Date 2021-06-14
Est. Completion 2026-06
Phase Phase 1

Sponsor

Montefiore Medical Center

280 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT05001750

The ClinicalTrials.gov registry entry for NCT05001750 describes a study currently listed as recruiting. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 84 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Montefiore Medical Center, which has 280 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 4 conditions, with Intracerebral Hemorrhage appearing as the primary indexed condition, and to 2 interventions — of which Long term (continuous) prophylactic antibiotics is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT05001750 reports 1 study location spanning 1 distinct geographic area — top geographies include New York. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT05001750 about?

NCT05001750 is a clinical study titled "Prophylactic Antibiotics Useful With Antibiotic Impregnated External Ventricular Drains (EVDs)?". The principal objective of this study is to compare the incidence of ventriculostomy related infections (VRIs) in patients who receive twenty-four hours of antibiotics, beginning no more than sixty minutes prior to EVD placement, to the incidence of VRIs in patients who also receive a pre-procedural...

What is the current status of trial NCT05001750?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 84 participants. The study started on 2021-06-14. Estimated completion is 2026-06.

What conditions does trial NCT05001750 study?

This clinical trial studies the following conditions: Intracerebral Hemorrhage, Subarachnoid Hemorrhage, Hydrocephalus, Ventriculitis, Cerebral. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT05001750?

The interventions under investigation include: Long term (continuous) prophylactic antibiotics (DRUG), 24 hours antibiotics (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT05001750?

This trial is sponsored by Montefiore Medical Center, which has 280 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT05001750 being conducted?

This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial