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COMPLETED Phase 3

Comparison of Qutenza (8% Capsaicin) With a Low-dose Capsaicin for Treatment of Nerve Pain After Surgery

NCT04967664 · View on ClinicalTrials.gov ↗

Study Summary

This is an interventional, Phase III, double-blind, randomized, controlled, parallel-group, multi-site, clinical trial to confirm the efficacy and safety of repeated topical application of Qutenza (capsaicin 8% topical system) versus low-dose capsaicin control (capsaicin 0.04% topical system) in subjects with moderate to severe postsurgical neuropathic pain (PSNP).

Interventions

  • DRUG Qutenza (capsaicin) 8% topical system
  • DRUG capsaicin 0.04% topical system

Study Locations (20)

Florida

  • South Lake Pain Institute — Clermont
  • University Clinical Research - DeLand Clinical Research Unit — DeLand
  • Florida Research Center, Inc. — Miami
  • Clinical Research of West Florida — Tampa

Kansas

  • Neuroscience Research Center, LLC — Overland Park
  • Kansas City Bone & Joint Clinic, P.A. — Overland Park

North Carolina

  • Accellacare — Wilmington
  • The Center for Clinical Research — Winston-Salem

Arizona

  • Tucson Orthopaedic Institute — Tucson

California

  • ILD Research Center — Vista

District of Columbia

  • International Spine, Pain, and Performance Center — Washington D.C.

Georgia

  • Drug Studies America — Marietta

Illinois

  • Rush University Medical Center — Chicago

Trial Details

FieldValue
Enrollment Target 409 participants
Start Date 2021-07-13
Est. Completion 2025-08-28
Phase Phase 3

Sponsor

Averitas Pharma

2 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT04967664

The ClinicalTrials.gov registry entry for NCT04967664 describes a study currently listed as completed. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 409 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Averitas Pharma, which has 2 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Post Surgical Neuropathic Pain appearing as the primary indexed condition, and to 2 interventions — of which Qutenza (capsaicin) 8% topical system is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT04967664 reports 20 study locations spanning 15 distinct geographic areas — top geographies include Florida, Kansas, North Carolina. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT04967664 about?

NCT04967664 is a clinical study titled "Comparison of Qutenza (8% Capsaicin) With a Low-dose Capsaicin for Treatment of Nerve Pain After Surgery". This is an interventional, Phase III, double-blind, randomized, controlled, parallel-group, multi-site, clinical trial to confirm the efficacy and safety of repeated topical application of Qutenza (capsaicin 8% topical system) versus low-dose capsaicin control (capsaicin 0.04% topical system) in sub...

What is the current status of trial NCT04967664?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 409 participants. The study started on 2021-07-13. Estimated completion is 2025-08-28.

What conditions does trial NCT04967664 study?

This clinical trial studies the following conditions: Post Surgical Neuropathic Pain. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT04967664?

The interventions under investigation include: Qutenza (capsaicin) 8% topical system (DRUG), capsaicin 0.04% topical system (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT04967664?

This trial is sponsored by Averitas Pharma, which has 2 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT04967664 being conducted?

This trial has 20 study locations across Arizona, California, District of Columbia, Florida, Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial