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NCT04947514 · ClinicalTrials.gov registry record · Phase 4

Use of Tranexamic Acid in Reduction Mammoplasty

A Phase 4 study of Venous Thromboembolism and Hematoma Postoperative, sponsored by Montefiore Medical Center.

Completed
Registry status
Phase 4
Development phase
98
Enrollment target
1
Study location

NCT04947514 is a Phase 4 study of Venous Thromboembolism and Hematoma Postoperative that has completed, run by Montefiore Medical Center. The registered enrollment target is 98 participants, below the 6,294-participant average among 47 other Venous Thromboembolism trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT04947514, a Phase 4 study of Venous Thromboembolism and Hematoma Postoperative, has completed, sponsored by Montefiore Medical Center.

COMPLETED
Registry status
Phase 4
Development phase
98 participants
Enrollment target
1
Study location

Study Summary

Breast reduction mammoplasty (BRM) is among the most commonly performed procedures in plastic surgery. However, postoperative hematoma is one of the most common complications following BRM. Hematoma-related complications include unplanned surgery, need for blood transfusion, wound healing issues, and unfavorable surgical outcomes. Tranexamic acid has emerged in the literature as a promising agent that reduces perioperative blood loss and need for transfusion. However, despite its consistently reported efficacy, low cost, and favorable safety profile, tranexamic acid remains underutilized in plastic surgery. The investigators propose a prospective, double-blinded randomized controlled study of the efficacy of tranexamic acid in reducing hematoma development in patients undergoing reduction mammoplasty. The investigators hope to contribute to the growing body of literature supporting tranexamic acid to reduce unwanted surgical bleeding.

Interventions

  • DRUG Tranexamic acid
  • OTHER Placebo (topical saline)

Study Locations (1)

New York

  • Montefiore Medical Center Hutchinson Metro Center Campus - The Bronx

Trial Details

FieldValue
Enrollment Target 98 participants
Start Date 2021-10-29
Est. Completion 2022-07-13
Phase Phase 4

Sponsor

Montefiore Medical Center

345 total trials

What the Registry Record Tells You About NCT04947514

The ClinicalTrials.gov registry entry for NCT04947514 describes a study currently listed as completed, categorized as Phase 4. The registered enrollment target is 98 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 6,294-participant average among 47 other Venous Thromboembolism trials with a reported enrollment target (98% lower). The listed sponsor is Montefiore Medical Center, which has 345 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Venous Thromboembolism appearing as the primary indexed condition, and to 2 interventions - of which Tranexamic acid is the first listed.

NCT04947514 reports 1 study location spanning 1 distinct geographic area - top geographies include New York.

Frequently Asked Questions

What is clinical trial NCT04947514 about?

NCT04947514 is a clinical study titled "Use of Tranexamic Acid in Reduction Mammoplasty". Breast reduction mammoplasty (BRM) is among the most commonly performed procedures in plastic surgery. However, postoperative hematoma is one of the most common complications following BRM. Hematoma-related complications include unplanned surgery, need for blood transfusion, wound healing issues, an...

What is the current status of trial NCT04947514?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 98 participants. The study started on 2021-10-29. Estimated completion is 2022-07-13.

What conditions does trial NCT04947514 study?

This clinical trial studies the following conditions: Venous Thromboembolism, Hematoma Postoperative.

What interventions are being tested in trial NCT04947514?

The interventions under investigation include: Tranexamic acid (DRUG), Placebo (topical saline) (OTHER).

Who is sponsoring clinical trial NCT04947514?

This trial is sponsored by Montefiore Medical Center, which has 345 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04947514 being conducted?

This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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