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NCT04920617 · ClinicalTrials.gov registry record · Phase 2
DPX-Survivac and Pembrolizumab With and Without Intermittent Low-Dose Cyclophosphamide, in Subjects With Relapsed/Refractory Diffuse Large B-Cell Lymphoma
A Phase 2 study of Refractory Diffuse Large B-Cell Lymphoma and Relapsed Diffuse Large B-cell Lymphoma, sponsored by ImmunoVaccine Technologies, Inc. (IMV Inc.).
- Recruiting
- Registry status
- Phase 2
- Development phase
- 102
- Enrollment target
- 20
- Study locations
NCT04920617 is a Phase 2 study of Refractory Diffuse Large B-Cell Lymphoma and Relapsed Diffuse Large B-cell Lymphoma that is actively recruiting participants, run by ImmunoVaccine Technologies, Inc. (IMV Inc.). The registered enrollment target is 102 participants, above the 61-participant average among 37 other Refractory Diffuse Large B-Cell Lymphoma trials with a reported enrollment target (67% higher). The trial reports 20 study locations across 13 states.
The verdict
NCT04920617, a Phase 2 study of Refractory Diffuse Large B-Cell Lymphoma and Relapsed Diffuse Large B-cell Lymphoma, is actively recruiting participants, sponsored by ImmunoVaccine Technologies, Inc. (IMV Inc.).
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 102 participants
- Enrollment target
- 20
- Study locations
Study Summary
This is a Phase 2b, randomized, open label study to assess the safety and efficacy of DPX-Survivac and pembrolizumab, with and without low-dose cyclophosphamide (CPA) in subjects with relapsed or refractory DLBCL.
Conditions Studied
Interventions
- DRUG Pembrolizumab
- DRUG DPX-Survivac
- DRUG CPA
Study Locations (20)
Florida
- Boca Raton Regional Hospital - Boca Raton
- BRCR Medical Center Inc. - Hollywood
- BRCR Medical Center Inc. - Plantation
- Comprehensive Hematology and Oncology - St. Petersburg
Ohio
- Gabrail Cancer Center Research - Canton
- University of Toledo Medical Center - Toledo
- Toledo Clinic Cancer Center - Toledo
Pennsylvania
- Allegheny Health Network (AHN) West Penn Hospital - Pittsburgh
- Reading Hospital - McGlinn Cancer Institute - West Reading
Victoria
- Epworth Freemasons Hospital - Melbourne
- Box Hill Hospital - Melbourne
California
- Compassionate Cancer Care Medical Group - Fountain Valley
Georgia
- Blood and Marrow Transplant Group of Georgia - Atlanta
Indiana
- Indiana University Health Melvin and Bren Simon Cancer Center - Indianapolis
Louisiana
- Tulane Cancer Center Office of Clinical Research - New Orleans
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 102 participants |
| Start Date | 2021-06-18 |
| Est. Completion | 2025-04 |
| Phase | Phase 2 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04920617
The ClinicalTrials.gov registry entry for NCT04920617 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 102 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 61-participant average among 37 other Refractory Diffuse Large B-Cell Lymphoma trials with a reported enrollment target (67% higher). The listed sponsor is ImmunoVaccine Technologies, Inc. (IMV Inc.), which has 6 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Refractory Diffuse Large B-Cell Lymphoma appearing as the primary indexed condition, and to 3 interventions - of which Pembrolizumab is the first listed.
NCT04920617 reports 20 study locations spanning 13 distinct geographic areas - top geographies include Florida, Ohio, Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT04920617 about?
NCT04920617 is a clinical study titled "DPX-Survivac and Pembrolizumab With and Without Intermittent Low-Dose Cyclophosphamide, in Subjects With Relapsed/Refractory Diffuse Large B-Cell Lymphoma". This is a Phase 2b, randomized, open label study to assess the safety and efficacy of DPX-Survivac and pembrolizumab, with and without low-dose cyclophosphamide (CPA) in subjects with relapsed or refractory DLBCL.
What is the current status of trial NCT04920617?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 102 participants. The study started on 2021-06-18. Estimated completion is 2025-04.
What conditions does trial NCT04920617 study?
This clinical trial studies the following conditions: Refractory Diffuse Large B-Cell Lymphoma, Relapsed Diffuse Large B-cell Lymphoma.
What interventions are being tested in trial NCT04920617?
The interventions under investigation include: Pembrolizumab (DRUG), DPX-Survivac (DRUG), CPA (DRUG).
Who is sponsoring clinical trial NCT04920617?
This trial is sponsored by ImmunoVaccine Technologies, Inc. (IMV Inc.), which has 6 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04920617 being conducted?
This trial has 20 study locations across California, Florida, Georgia, Indiana, Louisiana. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.