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A Study to Evaluate the Safety, Tolerability, and Efficacy of IMB-1018972 in Patients With Non-obstructive Hypertrophic Cardiomyopathy Trial
NCT04826185 · View on ClinicalTrials.gov ↗
Study Summary
The purpose of this study is to assess the safety, tolerability, and potential efficacy of IMB-1018972 in patients with non-obstructive HCM.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG IMB-1018972
Study Locations (14)
California
- Imbria Investigational Site — La Jolla
- Imbria Investigational Site — Los Angeles
- Imbria Investigational Site — San Francisco
Massachusetts
- Imbria Investigational Site — Boston
- Imbria Investigational Site — Burlington
Illinois
- Imbria Investigational Site — Chicago
Missouri
- Imbria Investigational Site — St Louis
New Jersey
- Imbria Investigational Site — Morristown
New York
- Imbria Investigational Site — New York
North Carolina
- Imbria Investigational Site — Charlotte
Oregon
- Imbria Investigational Site — Portland
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 67 participants |
| Start Date | 2021-06-14 |
| Est. Completion | 2023-09-18 |
| Phase | Phase 2 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04826185
The ClinicalTrials.gov registry entry for NCT04826185 describes a study currently listed as completed. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 67 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Imbria Pharmaceuticals, which has 2 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Non-obstructive Hypertrophic Cardiomyopathy appearing as the primary indexed condition, and to 2 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT04826185 reports 14 study locations spanning 11 distinct geographic areas — top geographies include California, Massachusetts, Illinois. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT04826185 about?
NCT04826185 is a clinical study titled "A Study to Evaluate the Safety, Tolerability, and Efficacy of IMB-1018972 in Patients With Non-obstructive Hypertrophic Cardiomyopathy Trial". The purpose of this study is to assess the safety, tolerability, and potential efficacy of IMB-1018972 in patients with non-obstructive HCM.
What is the current status of trial NCT04826185?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 67 participants. The study started on 2021-06-14. Estimated completion is 2023-09-18.
What conditions does trial NCT04826185 study?
This clinical trial studies the following conditions: Non-obstructive Hypertrophic Cardiomyopathy. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT04826185?
The interventions under investigation include: Placebo (DRUG), IMB-1018972 (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT04826185?
This trial is sponsored by Imbria Pharmaceuticals, which has 2 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT04826185 being conducted?
This trial has 14 study locations across California, Illinois, Massachusetts, Missouri, New Jersey. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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