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NCT04686799 · ClinicalTrials.gov registry record · Phase 1
Doxycycline for Elbow Tendinopathy
A Phase 1 study of Lateral Epicondylitis and Lateral Epicondylitis, Unspecified Elbow, sponsored by Hospital for Special Surgery, New York.
- Active
- Registry status
- Phase 1
- Development phase
- 25
- Enrollment target
- 1
- Study location
NCT04686799: Active Phase 1 study of Lateral Epicondylitis and Lateral Epicondylitis, Unspecified Elbow, sponsored by Hospital for Special Surgery, New York.
NCT04686799 is a Phase 1 study of Lateral Epicondylitis and Lateral Epicondylitis, Unspecified Elbow that is active but no longer recruiting, run by Hospital for Special Surgery, New York. The registered enrollment target is 25 participants, below the 124-participant average among 7 other Lateral Epicondylitis trials with a reported enrollment target (80% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04686799, a Phase 1 study of Lateral Epicondylitis and Lateral Epicondylitis, Unspecified Elbow, is active but no longer recruiting, sponsored by Hospital for Special Surgery, New York.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 1
- Development phase
- 25 participants
- Enrollment target
- 1
- Study location
Study Summary
To evaluate the feasibility of subantimicrobial -dose (SD) doxycycline to improve outcomes of nonsurgical management of elbow tendinopathy via matrix metalloproteinase (MMP) inhibition as well as evaluate if participants will be compliant to with prescribed medication and exercise treatment. Our working hypothesis is that patients with elbow tendinopathy will be receptive to treatment with SD-doxycycline and compliant with the prescribed treatment.
Primary Outcome
Compliance: At the end of the study, compliance will be calculated using the number of self-reported doses taken divided by the number of prescribed doses (twice daily x 7 days per week x 12 weeks = 168 doses).
Conditions Studied
Interventions
- DRUG Doxycycline Hyclate 20 MG
Study Locations (1)
New York
- Hospital for Special Surgery - New York
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 25 participants |
| Start Date | 2020-12-03 |
| Est. Completion | 2026-01 |
| Phase | Phase 1 |
What the registry record for NCT04686799 still lists
NCT04686799 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 25 participants, a relatively small participant target, below the 124-participant average among 7 other Lateral Epicondylitis trials with a reported enrollment target (80% lower).
The record links to 8 conditions, with Lateral Epicondylitis appearing as the primary indexed condition, and to 1 intervention - of which Doxycycline Hyclate 20 MG is the first listed.
NCT04686799 reports a single indexed study location in New York.
Frequently Asked Questions
What is clinical trial NCT04686799 about?
NCT04686799 is a clinical study titled "Doxycycline for Elbow Tendinopathy". To evaluate the feasibility of subantimicrobial -dose (SD) doxycycline to improve outcomes of nonsurgical management of elbow tendinopathy via matrix metalloproteinase (MMP) inhibition as well as evaluate if participants will be compliant to with prescribed medication and exercise treatment. Our wor...
What is the current status of trial NCT04686799?
This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 25 participants. The study started on 2020-12-03. Estimated completion is 2026-01.
What conditions does trial NCT04686799 study?
This clinical trial studies the following conditions: Lateral Epicondylitis, Lateral Epicondylitis, Unspecified Elbow, Lateral Epicondylitis, Left Elbow, Lateral Epicondylitis, Right Elbow, Lateral Epicondylitis (Tennis Elbow) Bilateral.
What interventions are being tested in trial NCT04686799?
The interventions under investigation include: Doxycycline Hyclate 20 MG (DRUG).
Who is sponsoring clinical trial NCT04686799?
This trial is sponsored by Hospital for Special Surgery, New York, which has 194 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04686799 being conducted?
This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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