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NCT04544475 · ClinicalTrials.gov registry record · NA

A Randomized, Single Center Pilot Study Comparing Hyaluronic Acid to Vaginal Estrogen for Treatment of Genitourinary Syndrome of Menopause

A NA study of Genitourinary Syndrome of Menopause (GSM), sponsored by NYU Langone Health.

Completed
Registry status
NA
Development phase
49
Enrollment target
1
Study location

NCT04544475 is a NA study of Genitourinary Syndrome of Menopause (GSM) that has completed, run by NYU Langone Health. The registered enrollment target is 49 participants. The trial reports 1 study location across 1 state.

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The verdict

NCT04544475, a NA study of Genitourinary Syndrome of Menopause (GSM), has completed, sponsored by NYU Langone Health.

COMPLETED
Registry status
NA
Development phase
49 participants
Enrollment target
1
Study location

Study Summary

Non-hormonal alternatives for the treatment of genitourinary syndrome of menopause (GSM) are needed. In this proposed trial, patients who are diagnosed with GSM will be randomized to receive either a hyaluronic acid (HLA) vaginal insert or vaginal estrogen topical cream for 12 weeks. There will be a baseline visit and an 12 week follow up visit, at which points the patient will undergo a detailed history and physical examination including a pelvic exam, vaginal pH sampling, vaginal cell sample for microscopic analysis, and will fill out a vulvovaginal symptom questionnaire (VSQ). These study arms will be analyzed to assess the efficacy of HLA as compared to the gold standard of vaginal estrogen to treat GSM symptoms.

Interventions

  • DEVICE Revaree
  • DRUG Estrace

Study Locations (1)

New York

  • NYU Langone Health - New York

Trial Details

FieldValue
Enrollment Target 49 participants
Start Date 2021-09-01
Est. Completion 2022-10-03
Phase NA

Sponsor

NYU Langone Health

1,164 total trials

What the Registry Record Tells You About NCT04544475

The ClinicalTrials.gov registry entry for NCT04544475 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 49 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is NYU Langone Health, which has 1,164 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Genitourinary Syndrome of Menopause (GSM) appearing as the primary indexed condition, and to 2 interventions - of which Revaree is the first listed.

NCT04544475 reports 1 study location spanning 1 distinct geographic area - top geographies include New York.

Frequently Asked Questions

What is clinical trial NCT04544475 about?

NCT04544475 is a clinical study titled "A Randomized, Single Center Pilot Study Comparing Hyaluronic Acid to Vaginal Estrogen for Treatment of Genitourinary Syndrome of Menopause". Non-hormonal alternatives for the treatment of genitourinary syndrome of menopause (GSM) are needed. In this proposed trial, patients who are diagnosed with GSM will be randomized to receive either a hyaluronic acid (HLA) vaginal insert or vaginal estrogen topical cream for 12 weeks. There will be a...

What is the current status of trial NCT04544475?

This trial is currently completed. It is a NA study. The enrollment target is 49 participants. The study started on 2021-09-01. Estimated completion is 2022-10-03.

What conditions does trial NCT04544475 study?

This clinical trial studies the following conditions: Genitourinary Syndrome of Menopause (GSM).

What interventions are being tested in trial NCT04544475?

The interventions under investigation include: Revaree (DEVICE), Estrace (DRUG).

Who is sponsoring clinical trial NCT04544475?

This trial is sponsored by NYU Langone Health, which has 1,164 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04544475 being conducted?

This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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