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NCT04182607 · ClinicalTrials.gov registry record

Donor Outcomes Following Hand-Assisted and Robotic Living Donor Nephrectomy: a Retrospective Review

A clinical trial of Kidney Diseases and Transplant, sponsored by Methodist Health System.

Recruiting
Registry status
240
Enrollment target
1
Study location

NCT04182607 is a study of Kidney Diseases and Transplant that is actively recruiting participants, run by Methodist Health System. The registered enrollment target is 240 participants, below the 1,779-participant average among 38 other Kidney Diseases trials with a reported enrollment target (87% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT04182607, a study of Kidney Diseases and Transplant, is actively recruiting participants, sponsored by Methodist Health System.

RECRUITING
Registry status
240 participants
Enrollment target
1
Study location

Study Summary

1.1. Background: Renal transplantation is the treatment of choice for eligible patients with end-stage renal disease. It provides better outcomes in terms of life expectancy and quality of life than dialysis (Liu, Narins, Maley, Frank, \& Lallas, 2012). Kidney transplants from living donors also have additional benefits in terms of graft function and survival compared to transplants from cadaver donors (Galvani et al., 2012). Living donor transplants provide an opportunity to have good quality grafts and to perform the procedure when the recipient is in an optimal clinical status (Creta et al., 2019). Laparoscopic donor nephrectomy was first introduced in 1995 and is currently accepted as the gold standard for kidney procurement from living donors. The first worldwide robotic assisted laparoscopic donor nephrectomy was performed in 2000 by Horgan et al. (Horgan et al., 2007). The main obstacle to living donation is the exposure of a healthy subject to the risks of a major surgical intervention. Therefore, efforts have been made to reduce complications and postoperative pain, achieve faster recovery, and minimize the surgical incisions. Minimally invasive procedures like hand-assisted and robotic approaches greatly enhance living donation rates, and in 2001 the number of living donors exceeded the number of cadaver donors (Horgan et al., 2007). 1.2. Aim(s)/Objective(s): The objective of this study is to compare intra- and postoperative patient outcomes of kidney donors following hand-assisted and robotic kidney transplants at a single center. 1.3. Rationale for the study: More research is needed regarding the differences between minimally invasive approaches to kidney transplantation.

Interventions

  • PROCEDURE kidney transplant

Study Locations (1)

Texas

  • The Liver Institute at Methodist Dallas Medical Center - Dallas

Trial Details

FieldValue
Enrollment Target 240 participants
Start Date 2019-11-06
Est. Completion 2025-11

Sponsor

Methodist Health System

125 total trials

What the Registry Record Tells You About NCT04182607

The ClinicalTrials.gov registry entry for NCT04182607 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 240 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 1,779-participant average among 38 other Kidney Diseases trials with a reported enrollment target (87% lower). The listed sponsor is Methodist Health System, which has 125 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Kidney Diseases appearing as the primary indexed condition, and to 1 intervention - of which kidney transplant is the first listed.

NCT04182607 reports 1 study location spanning 1 distinct geographic area - top geographies include Texas.

Frequently Asked Questions

What is clinical trial NCT04182607 about?

NCT04182607 is a clinical study titled "Donor Outcomes Following Hand-Assisted and Robotic Living Donor Nephrectomy: a Retrospective Review". 1.1. Background: Renal transplantation is the treatment of choice for eligible patients with end-stage renal disease. It provides better outcomes in terms of life expectancy and quality of life than dialysis (Liu, Narins, Maley, Frank, \& Lallas, 2012). Kidney transplants from living donors also hav...

What is the current status of trial NCT04182607?

This trial is currently recruiting. The enrollment target is 240 participants. The study started on 2019-11-06. Estimated completion is 2025-11.

What conditions does trial NCT04182607 study?

This clinical trial studies the following conditions: Kidney Diseases, Transplant.

What interventions are being tested in trial NCT04182607?

The interventions under investigation include: kidney transplant (PROCEDURE).

Who is sponsoring clinical trial NCT04182607?

This trial is sponsored by Methodist Health System, which has 125 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04182607 being conducted?

This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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