Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT04012996 · ClinicalTrials.gov registry record · NA
2-level Cervical Disc Replacement Comparing Prodisc C SK & Vivo to Mobi-C
A NA study of Symptomatic Cervical Disc Disease, sponsored by Centinel Spine.
- Active
- Registry status
- NA
- Development phase
- 390
- Enrollment target
- 20
- Study locations
NCT04012996: Active NA study of Symptomatic Cervical Disc Disease, sponsored by Centinel Spine.
NCT04012996 is a NA study of Symptomatic Cervical Disc Disease that is active but no longer recruiting, run by Centinel Spine. The registered enrollment target is 390 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (72% lower). The trial reports 20 study locations across 12 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04012996, a NA study of Symptomatic Cervical Disc Disease, is active but no longer recruiting, sponsored by Centinel Spine.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 390 participants
- Enrollment target
- 20
- Study locations
Study Summary
A multi-center, prospective, randomized, controlled comparison of the prodisc C SK and prodisc C Vivo to the control, a similar, legally marketed total disc replacement device in subjects with symptomatic cervical disc disease (SCDD).
Primary Outcome
Includes assessments such as NDI and neurological improvement.
Conditions Studied
Interventions
- DEVICE prodisc C SK and/or Vivo
- DEVICE Mobi-C Cervical Disc
Study Locations (20)
California
- Todd Lanman, MD, Inc. - Beverly Hills
- Doctors Outpatient Center for Surgery - Los Angeles
- Sutter Health - Palo Alto Medical Foundation - Palo Alto
- Sutter Health - Sacramento
Florida
- St. Vincent's Neurosurgery - Jacksonville
- Kennedy-White Orthopaedic Center - Sarasota
- University of South Florida - Tampa
- Florida Orthopaedic Institute - Temple Terrace
Colorado
- HCA Healthcare - Lone Tree
- Sky Ridge Medical Center Campus - Lone Tree
- Center for Spine and Orthopedics, Scientific Education and Research Foundation - Thornton
Arizona
- Flagstaff Bone and Joint - Flagstaff
District of Columbia
- Georgetown University Hospital - Washington D.C.
Indiana
- Indiana Spine Group - Carmel
Kentucky
- Orthopaedic Institute of Western Kentucky - Paducah
Louisiana
- Spine Institute of Louisiana - Shreveport
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 390 participants |
| Start Date | 2019-08-05 |
| Est. Completion | 2028-05-13 |
| Phase | NA |
What the registry record for NCT04012996 still lists
NCT04012996 is an interventional study that assigns participants to a tested intervention. The registered 390 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (72% lower).
The record links to 1 condition, with Symptomatic Cervical Disc Disease appearing as the primary indexed condition, and to 2 interventions - of which prodisc C SK and/or Vivo is the first listed.
NCT04012996 names 20 study sites across 12 states, led by California, Florida, Colorado.
Frequently Asked Questions
What is clinical trial NCT04012996 about?
NCT04012996 is a clinical study titled "2-level Cervical Disc Replacement Comparing Prodisc C SK & Vivo to Mobi-C". A multi-center, prospective, randomized, controlled comparison of the prodisc C SK and prodisc C Vivo to the control, a similar, legally marketed total disc replacement device in subjects with symptomatic cervical disc disease (SCDD).
What is the current status of trial NCT04012996?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 390 participants. The study started on 2019-08-05. Estimated completion is 2028-05-13.
What conditions does trial NCT04012996 study?
This clinical trial studies the following conditions: Symptomatic Cervical Disc Disease.
What interventions are being tested in trial NCT04012996?
The interventions under investigation include: prodisc C SK and/or Vivo (DEVICE), Mobi-C Cervical Disc (DEVICE).
Who is sponsoring clinical trial NCT04012996?
This trial is sponsored by Centinel Spine, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04012996 being conducted?
This trial has 20 study locations across Arizona, California, Colorado, District of Columbia, Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Symptomatic Cervical Disc Disease
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04012996's enrollment target sits among peer trials
390 269th of 2000 higher than 1,731 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT00397111 · 390 participants
Development of Magnetic Resonance Imaging Techniques for Studying Mood and Anxiety Disorders
- NCT05335928 · 390 participants · Phase 3
Abatacept in Immune Checkpoint Inhibitor Myocarditis
- NCT05445960 · 390 participants · NA
Correlation Between Intraoperative Tourniquet Use and Limb pH, Functional Measures and Patient-reported Outcomes After Ankle Fracture Surgery
- NCT05997615 · 390 participants · Phase 1
Safety, Pharmacokinetics, and Preliminary Efficacy of VIR-5500 (AMX-500) in Prostate Cancer
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI