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NCT03994406 · ClinicalTrials.gov registry record · Phase 2

Prolongation of Contact Lens Comfortable Wear Duration by CLM2 Topical Gel

A Phase 2 study of Contact Lens Discomfort and Contact Lens-induced Corneal Disorder, sponsored by Glia.

Completed
Registry status
Phase 2
Development phase
30
Enrollment target
1
Study location

NCT03994406: Completed Phase 2 study of Contact Lens Discomfort and Contact Lens-induced Corneal Disorder, sponsored by Glia.

NCT03994406 is a Phase 2 study of Contact Lens Discomfort and Contact Lens-induced Corneal Disorder that has completed, run by Glia. The registered enrollment target is 30 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (77% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT03994406, a Phase 2 study of Contact Lens Discomfort and Contact Lens-induced Corneal Disorder, has completed, sponsored by Glia.

COMPLETED
Registry status
Phase 2
Development phase
30 participants
Enrollment target
1
Study location

Study Summary

This study compares contact lens comfortable wear duration, and signs and symptoms of contact lens discomfort, test versus control.

Primary Outcome

Change in total hours per day

Interventions

  • DRUG CLM2 topical gel
  • DRUG Placebo topical gel

Study Locations (1)

California

  • UC Berkeley Clinical Research Center - Berkeley

Trial Details

FieldValue
Enrollment Target 30 participants
Start Date 2019-06-27
Est. Completion 2019-10-30
Phase Phase 2
Glia

3 total trials

What the finished NCT03994406 record still lists

NCT03994406 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (77% lower).

The record links to 4 conditions, with Contact Lens Discomfort appearing as the primary indexed condition, and to 2 interventions - of which CLM2 topical gel is the first listed.

NCT03994406 reports a single indexed study location in California.

Frequently Asked Questions

What is clinical trial NCT03994406 about?

NCT03994406 is a clinical study titled "Prolongation of Contact Lens Comfortable Wear Duration by CLM2 Topical Gel". This study compares contact lens comfortable wear duration, and signs and symptoms of contact lens discomfort, test versus control.

What is the current status of trial NCT03994406?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 30 participants. The study started on 2019-06-27. Estimated completion is 2019-10-30.

What conditions does trial NCT03994406 study?

This clinical trial studies the following conditions: Contact Lens Discomfort, Contact Lens-induced Corneal Disorder, Contact Lens Acute Red Eye, Contact Lens-induced Corneal Fluorescein Staining.

What interventions are being tested in trial NCT03994406?

The interventions under investigation include: CLM2 topical gel (DRUG), Placebo topical gel (DRUG).

Who is sponsoring clinical trial NCT03994406?

This trial is sponsored by Glia, which has 3 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03994406 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Contact Lens Discomfort

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT03994406's enrollment target sits among peer trials

30 1582nd of 2000 higher than 332 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT03994406, the US trial registry maintained by the National Library of Medicine. NCT03994406 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.