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NCT03946059 · ClinicalTrials.gov registry record · NA

Measuring Plasticity in SFC/dACC Following Theta-Burst-Stimulation Using TMS

A NA study of Cognitive Control, sponsored by University of California, San Diego.

Completed
Registry status
NA
Development phase
25
Enrollment target
1
Study location

NCT03946059 is a NA study of Cognitive Control that has completed, run by University of California, San Diego. The registered enrollment target is 25 participants. The trial reports 1 study location across 1 state.

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The verdict

NCT03946059, a NA study of Cognitive Control, has completed, sponsored by University of California, San Diego.

COMPLETED
Registry status
NA
Development phase
25 participants
Enrollment target
1
Study location

Study Summary

This is a study to determine whether particular forms of brain-stimulation, applied to superior frontal cortex/preSMA can affect cognition and associated frontal theta oscillations. To perform this study, the investigators first measure brain activity and cognitive performance using "BrainE", a cognitive task platform that assesses cognition on sustained attention, response inhibition, working memory, interference processing and emotion processing assessments. Next, the investigators apply brain-stimulation over a mid-frontal region associated with these tasks (mid-line frontal activity overlying superior frontal cortex/pre-SMA area). Finally, human subjects perform the "BrainE" task assessments again immediately after the brain-stimulation. The investigators compare the effects of brain stimulation on average frontal activity evoked across the cognitive tasks, and on the cognitive performance averaged across tasks. The investigators primarily compare the effects of two types of brain-stimulation against each other: intermittent Theta-Burst Stimulation (a protocol designed to excite brain activity) and continuous Theta-Burst-Stimulation (a stimulation protocol designed to inhibit brain activity).

Conditions Studied

Interventions

  • DEVICE iTBS then cTBS
  • DEVICE cTBS then iTBS

Study Locations (1)

California

  • Altman Clinical & Translational Research Institute - La Jolla

Trial Details

FieldValue
Enrollment Target 25 participants
Start Date 2019-04-30
Est. Completion 2019-10-30
Phase NA

Sponsor

University of California, San Diego

775 total trials

What the Registry Record Tells You About NCT03946059

The ClinicalTrials.gov registry entry for NCT03946059 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 25 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of California, San Diego, which has 775 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Cognitive Control appearing as the primary indexed condition, and to 2 interventions - of which iTBS then cTBS is the first listed.

NCT03946059 reports 1 study location spanning 1 distinct geographic area - top geographies include California.

Frequently Asked Questions

What is clinical trial NCT03946059 about?

NCT03946059 is a clinical study titled "Measuring Plasticity in SFC/dACC Following Theta-Burst-Stimulation Using TMS". This is a study to determine whether particular forms of brain-stimulation, applied to superior frontal cortex/preSMA can affect cognition and associated frontal theta oscillations. To perform this study, the investigators first measure brain activity and cognitive performance using "BrainE", a cogn...

What is the current status of trial NCT03946059?

This trial is currently completed. It is a NA study. The enrollment target is 25 participants. The study started on 2019-04-30. Estimated completion is 2019-10-30.

What conditions does trial NCT03946059 study?

This clinical trial studies the following conditions: Cognitive Control.

What interventions are being tested in trial NCT03946059?

The interventions under investigation include: iTBS then cTBS (DEVICE), cTBS then iTBS (DEVICE).

Who is sponsoring clinical trial NCT03946059?

This trial is sponsored by University of California, San Diego, which has 775 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03946059 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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