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COMPLETED Early Phase 1

Neural Mechanisms of Cannabinoid-impaired Decision-Making in Emerging Adults

NCT03944954 · View on ClinicalTrials.gov ↗

Study Summary

Emerging adults are a particularly vulnerable group for experiencing the immediate and potentially lifelong negative impacts of habitual cannabis use, and trends suggest that cannabis use disorder (CUD) will soon escalate in this population. The proposed research will combine clinical pharmacology, non-invasive brain stimulation, and neuroimaging techniques to establish the brain mechanisms of cannabinoid-impaired decision-making processes in emerging adults with CUD. Results from this project will inform CUD prevention/treatment efforts in this high-risk group and address a growing public health concern.

Interventions

  • DEVICE Placebo TMS Sham
  • DRUG Marinol 10Mg Capsule TMS Sham
  • DRUG Marinol 30Mg Capsule TMS Sham
  • DEVICE Placebo TMS Real
  • OTHER Marinol 10Mg Capsule TMS Real

Study Locations (1)

Kentucky

  • Neurobehavioral Systems Lab of the University of Kentucky College of Medicine — Lexington

Trial Details

FieldValue
Enrollment Target 66 participants
Start Date 2017-07-15
Est. Completion 2023-12-13
Phase Early Phase 1

Sponsor

Michael J. Wesley, PhD

2 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT03944954

The ClinicalTrials.gov registry entry for NCT03944954 describes a study currently listed as completed. It is categorized as Early Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 66 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Michael J. Wesley, PhD, which has 2 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 3 conditions, with Substance-Related Disorders appearing as the primary indexed condition, and to 5 interventions — of which Placebo TMS Sham is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT03944954 reports 1 study location spanning 1 distinct geographic area — top geographies include Kentucky. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT03944954 about?

NCT03944954 is a clinical study titled "Neural Mechanisms of Cannabinoid-impaired Decision-Making in Emerging Adults". Emerging adults are a particularly vulnerable group for experiencing the immediate and potentially lifelong negative impacts of habitual cannabis use, and trends suggest that cannabis use disorder (CUD) will soon escalate in this population. The proposed research will combine clinical pharmacology, ...

What is the current status of trial NCT03944954?

This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 66 participants. The study started on 2017-07-15. Estimated completion is 2023-12-13.

What conditions does trial NCT03944954 study?

This clinical trial studies the following conditions: Substance-Related Disorders, Behavior Problem, Neurosciences. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT03944954?

The interventions under investigation include: Placebo TMS Sham (DEVICE), Marinol 10Mg Capsule TMS Sham (DRUG), Marinol 30Mg Capsule TMS Sham (DRUG), Placebo TMS Real (DEVICE), Marinol 10Mg Capsule TMS Real (OTHER). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT03944954?

This trial is sponsored by Michael J. Wesley, PhD, which has 2 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT03944954 being conducted?

This trial has 1 study location across Kentucky. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial