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Autologous Adult Adipose-Derived Regenerative Cell Injection Into Chronic Partial-Thickness Rotator Cuff Tears
NCT03752827 · View on ClinicalTrials.gov ↗
Study Summary
The purpose of this investigation is to evaluate the safety and superior effectiveness in functional improvement in patients with partial-thickness rotator cuff tears (PTRCTs) after the administration of a single injection of adipose-derived regenerative cells (ADRCs) into the partial-thickness rotator cuff tear compared to the administration of a single corticosteroid injection into the associated subacromial space.
Conditions Studied
Interventions
- DRUG Corticosteroid
- DEVICE Adipose Derived Regenerative Cells
Study Locations (14)
Florida
- Sports and Orthopedic Center — Coral Springs
- Universal Axon Clinical Research — Doral
- Shrock Clinical Research — Fort Lauderdale
- Andrews Institute for Orthopaedics and Sports Medicine — Gulf Breeze
California
- Biosolutions Clinical Research Center — La Mesa
- Lotus Clinical Research, LLC — Pasadena
Texas
- HD Research — Houston
- Texas Plastic Surgery — San Antonio
Arizona
- Arizona Research Center — Phoenix
Georgia
- Georgia Institute for Clinical Research — Marietta
Louisiana
- Tulane University School of Medicine — New Orleans
Michigan
- University of Michigan — Ann Arbor
North Dakota
- Sanford Medical Center — Fargo
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 168 participants |
| Start Date | 2019-05-13 |
| Est. Completion | 2025-12 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT03752827
The ClinicalTrials.gov registry entry for NCT03752827 describes a study currently listed as active not recruiting. It is categorized as NA, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 168 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is InGeneron, which has 3 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 2 conditions, with Rotator Cuff Tear appearing as the primary indexed condition, and to 2 interventions — of which Corticosteroid is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT03752827 reports 14 study locations spanning 9 distinct geographic areas — top geographies include Florida, California, Texas. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT03752827 about?
NCT03752827 is a clinical study titled "Autologous Adult Adipose-Derived Regenerative Cell Injection Into Chronic Partial-Thickness Rotator Cuff Tears". The purpose of this investigation is to evaluate the safety and superior effectiveness in functional improvement in patients with partial-thickness rotator cuff tears (PTRCTs) after the administration of a single injection of adipose-derived regenerative cells (ADRCs) into the partial-thickness rota...
What is the current status of trial NCT03752827?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 168 participants. The study started on 2019-05-13. Estimated completion is 2025-12.
What conditions does trial NCT03752827 study?
This clinical trial studies the following conditions: Rotator Cuff Tear, Rotator Cuff Tendinitis. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT03752827?
The interventions under investigation include: Corticosteroid (DRUG), Adipose Derived Regenerative Cells (DEVICE). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT03752827?
This trial is sponsored by InGeneron, which has 3 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT03752827 being conducted?
This trial has 14 study locations across Arizona, California, Florida, Georgia, Louisiana. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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