Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT03730454 · ClinicalTrials.gov registry record · NA
Transanastomotic Tube for Proximal Esophageal Atresia With Distal Tracheoesophageal Fistula Repair
A NA study of Esophageal Atresia and Tracheoesophageal Fistula, sponsored by Phoenix Children's Hospital.
- Active
- Registry status
- NA
- Development phase
- 142
- Enrollment target
- 10
- Study locations
NCT03730454: Active NA study of Esophageal Atresia and Tracheoesophageal Fistula, sponsored by Phoenix Children's Hospital.
NCT03730454 is a NA study of Esophageal Atresia and Tracheoesophageal Fistula that is active but no longer recruiting, run by Phoenix Children's Hospital. The registered enrollment target is 142 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (90% lower). The trial reports 10 study locations across 7 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03730454, a NA study of Esophageal Atresia and Tracheoesophageal Fistula, is active but no longer recruiting, sponsored by Phoenix Children's Hospital.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 142 participants
- Enrollment target
- 10
- Study locations
Study Summary
This trial will compare the effectiveness of two common surgical practices for Type C esophageal atresia repair: esophageal atresia (EA) with distal tracheoesophageal fistula (TEF). Infants with EA/TEF requiring surgical intervention will be recruited. Subjects will be randomized to either repair with or without transanstomotic tube (TT) during esophageal anastomosis creation. Primary outcome is symptomatic anastomotic stricture development requiring dilation within 12 months.
Primary Outcome
Symptomatic anastomotic stricture requiring dilation
Conditions Studied
Interventions
- DEVICE Transanastomotic Tube (5FR)
- OTHER No Transanastomotic Tube
Study Locations (10)
California
- Children's Hospital Los Angeles - Los Angeles
- Rady Children's Hospital - San Diego
- Benioff Children's Hospital - San Francisco
- Lucile Packard Children's Hospital - Stanford
Arizona
- Phoenix Children's Hospital - Phoenix
Colorado
- Children's Hospital Colorado - Aurora
Oregon
- Doernbecher Children's Hospital - Portland
Texas
- Children's Medical Center - Dallas
Utah
- Primary Children's Hospital - Salt Lake City
Washington
- Seattle Children's Hospital - Seattle
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 142 participants |
| Start Date | 2018-05-11 |
| Est. Completion | 2026-02-28 |
| Phase | NA |
What the registry record for NCT03730454 still lists
NCT03730454 is an interventional study that assigns participants to a tested intervention. The registered 142 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (90% lower).
The record links to 2 conditions, with Esophageal Atresia appearing as the primary indexed condition, and to 2 interventions - of which Transanastomotic Tube (5FR) is the first listed.
NCT03730454 lists 10 locations in 7 states (California, Arizona, Colorado).
Frequently Asked Questions
What is clinical trial NCT03730454 about?
NCT03730454 is a clinical study titled "Transanastomotic Tube for Proximal Esophageal Atresia With Distal Tracheoesophageal Fistula Repair". This trial will compare the effectiveness of two common surgical practices for Type C esophageal atresia repair: esophageal atresia (EA) with distal tracheoesophageal fistula (TEF). Infants with EA/TEF requiring surgical intervention will be recruited. Subjects will be randomized to either repair wi...
What is the current status of trial NCT03730454?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 142 participants. The study started on 2018-05-11. Estimated completion is 2026-02-28.
What conditions does trial NCT03730454 study?
This clinical trial studies the following conditions: Esophageal Atresia, Tracheoesophageal Fistula.
What interventions are being tested in trial NCT03730454?
The interventions under investigation include: Transanastomotic Tube (5FR) (DEVICE), No Transanastomotic Tube (OTHER).
Who is sponsoring clinical trial NCT03730454?
This trial is sponsored by Phoenix Children's Hospital, which has 26 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03730454 being conducted?
This trial has 10 study locations across Arizona, California, Colorado, Oregon, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03730454's enrollment target sits among peer trials
142 711th of 2000 higher than 1,289 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT03933631 · 142 participants · Phase 3
Pilocarpine Use After Kahook Goniotomy
- NCT04938349 · 142 participants · NA
Dual Task Perturbation Training for OAwMCI
- NCT06117254 · 142 participants · NA
Hearing Aids for Veterans With Functional Hearing Difficulties
- NCT06463665 · 142 participants · Phase 2
Efficacy & Safety of Olvimulogene Nanivacirepvec & Platinum-doublet + Physician's Choice of Immune Checkpoint Inhibitor Compared to Docetaxel in NSCL Cancer
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI