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NCT03562637 · ClinicalTrials.gov registry record · Phase 3

Study of Adagloxad Simolenin (OBI-822)/OBI-821 in the Adjuvant Treatment of Patients With Globo H Positive TNBC

A Phase 3 study of Triple Negative Breast Cancer, sponsored by OBI Pharma.

Active
Registry status
Phase 3
Development phase
575
Enrollment target
20
Study locations

NCT03562637 is a Phase 3 study of Triple Negative Breast Cancer that is active but no longer recruiting, run by OBI Pharma. The registered enrollment target is 575 participants, above the 242-participant average among 118 other Triple Negative Breast Cancer trials with a reported enrollment target (138% higher). The trial reports 20 study locations across 15 states.

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The verdict

NCT03562637, a Phase 3 study of Triple Negative Breast Cancer, is active but no longer recruiting, sponsored by OBI Pharma.

ACTIVE NOT RECRUITING
Registry status
Phase 3
Development phase
575 participants
Enrollment target
20
Study locations

Study Summary

The GLORIA study is a Phase III, randomized, open-label study to prospectively evaluate the efficacy and safety of adagloxad simolenin (OBI 822)/OBI-821 in the adjuvant treatment of patients with high risk, early stage Globo-H Positive TNBC.

Interventions

  • OTHER Standard of care treatment
  • BIOLOGICAL adagloxad simolenin combined with OBI-821
  • DEVICE Globo H IHC Assay

Study Locations (20)

California

  • Moores UCSD Cancer Center - La Jolla
  • Kaiser Permanente Medical Center - San Diego
  • UCSF Helen Diller Family Comprehensive Cancer Centre - San Francisco

Other

  • St Vincent's Hospital Sydney - Darlinghurst
  • Gosford Hospital - Gosford
  • St John of God Murdoch Hospital - Murdoch

Victoria

  • Victoria Breast & Oncology Care - East Melbourne
  • Cabrini Malvern - Malvern

Florida

  • Miami Cancer Institute - Miami

Illinois

  • University of Chicago Medical - Chicago

Maryland

  • University of Maryland Greenbaum Comprehensive Cancer Center - Baltimore

Michigan

  • Henry Ford Medical Center - Detroit

New Jersey

  • Rutgers Cancer Institute of New Jersey - New Brunswick

Trial Details

FieldValue
Enrollment Target 575 participants
Start Date 2018-12-05
Est. Completion 2027-12-30
Phase Phase 3

Sponsor

OBI Pharma

7 total trials

What the Registry Record Tells You About NCT03562637

The ClinicalTrials.gov registry entry for NCT03562637 describes a study currently listed as active not recruiting, categorized as Phase 3. The registered enrollment target is 575 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 242-participant average among 118 other Triple Negative Breast Cancer trials with a reported enrollment target (138% higher). The listed sponsor is OBI Pharma, which has 7 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Triple Negative Breast Cancer appearing as the primary indexed condition, and to 3 interventions - of which Standard of care treatment is the first listed.

NCT03562637 reports 20 study locations spanning 15 distinct geographic areas - top geographies include California, Other, Victoria.

Frequently Asked Questions

What is clinical trial NCT03562637 about?

NCT03562637 is a clinical study titled "Study of Adagloxad Simolenin (OBI-822)/OBI-821 in the Adjuvant Treatment of Patients With Globo H Positive TNBC". The GLORIA study is a Phase III, randomized, open-label study to prospectively evaluate the efficacy and safety of adagloxad simolenin (OBI 822)/OBI-821 in the adjuvant treatment of patients with high risk, early stage Globo-H Positive TNBC.

What is the current status of trial NCT03562637?

This trial is currently active not recruiting. It is a Phase 3 study. The enrollment target is 575 participants. The study started on 2018-12-05. Estimated completion is 2027-12-30.

What conditions does trial NCT03562637 study?

This clinical trial studies the following conditions: Triple Negative Breast Cancer.

What interventions are being tested in trial NCT03562637?

The interventions under investigation include: Standard of care treatment (OTHER), adagloxad simolenin combined with OBI-821 (BIOLOGICAL), Globo H IHC Assay (DEVICE).

Who is sponsoring clinical trial NCT03562637?

This trial is sponsored by OBI Pharma, which has 7 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03562637 being conducted?

This trial has 20 study locations across California, Florida, Illinois, Maryland, Michigan. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.