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RECRUITING NA

Tailored Axillary Surgery With or Without Axillary Lymph Node Dissection Followed by Radiotherapy in Patients With Clinically Node-positive Breast Cancer (TAXIS)

NCT03513614 · View on ClinicalTrials.gov ↗

Study Summary

RATIONALE: The use of tailored axillary dissection as a tailored procedure will avoid surgical overtreatment by selectively removing the lymph nodes that are affected by the cancer, thereby sparing many women the unnecessary complications of a radical surgery, providing a better quality of life while keeping the same efficacy. PURPOSE: The phase III trial is evaluating the optimal treatment for breast cancer patients in terms of surgery and radiotherapy.

Interventions

  • PROCEDURE Tailored axillary surgery - both Arms
  • RADIATION Radiotherapy - Arm A
  • RADIATION Radiotherapy - Arm B

Study Locations (20)

Other

  • Institute of Oncology "Angel H. Roffo — Buenos Aires
  • Krankenhaus Dornbirn — Dornbirn
  • Landeskrankenhaus Feldkirch — Feldkirch
  • Medical University of Innsbruck, Department of Gynecology — Innsbruck
  • Ordens Kinikum Linz, Barmherzige Schwestern — Linz
  • Universitätsklinik für Frauenheilkunde und Geburtshilfe; Landeskrankenhaus Salzburg der PMU — Salzburg
  • Medizinische Universität Wien - Klinik für Chirurgie — Vienna
  • Medizinische Universität Wien - Universitätsklinik für Frauenheilkunde — Vienna
  • Hanusch Hospital Vienna — Vienna
  • Klinikum Wels-Grieskrichen GmbH — Wels
  • CIUSSS du Centre Ouest-de-l'Île-de-Montréal, Jewish General Hospital — Montreal
  • Breast Centre of Clinical Hospital — Rijeka
  • HRUHC Sestre milosdrnice — Zagreb
  • Ev. Waldkrankenhaus Spandau — Berlin
  • KEM | Evang. Kliniken Essen-Mitte gGmbH — Essen
  • Niels-Stensen-Kliniken Franziskus-Hospital Harderberg — Georgsmarienhütte

Maryland

  • Walter Reed National Military Medical Center — Bethesda

North Carolina

  • Duke University/Duke Cancer Center — Durham

Washington

  • Swedish Cancer Institute — Seattle

Santa Fe Province

  • Sanatorio Parque Breast Cancer Center — Rosario

Trial Details

FieldValue
Enrollment Target 1,500 participants
Start Date 2018-08-07
Est. Completion 2036-12
Phase NA

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT03513614

The ClinicalTrials.gov registry entry for NCT03513614 describes a study currently listed as recruiting. It is categorized as NA, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 1,500 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University Hospital, Basel, Switzerland, which has 10 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Node-positive Breast Cancer appearing as the primary indexed condition, and to 3 interventions — of which Tailored axillary surgery - both Arms is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT03513614 reports 20 study locations spanning 5 distinct geographic areas — top geographies include Other, Maryland, North Carolina. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT03513614 about?

NCT03513614 is a clinical study titled "Tailored Axillary Surgery With or Without Axillary Lymph Node Dissection Followed by Radiotherapy in Patients With Clinically Node-positive Breast Cancer (TAXIS)". RATIONALE: The use of tailored axillary dissection as a tailored procedure will avoid surgical overtreatment by selectively removing the lymph nodes that are affected by the cancer, thereby sparing many women the unnecessary complications of a radical surgery, providing a better quality of life whil...

What is the current status of trial NCT03513614?

This trial is currently recruiting. It is a NA study. The enrollment target is 1,500 participants. The study started on 2018-08-07. Estimated completion is 2036-12.

What conditions does trial NCT03513614 study?

This clinical trial studies the following conditions: Node-positive Breast Cancer. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT03513614?

The interventions under investigation include: Tailored axillary surgery - both Arms (PROCEDURE), Radiotherapy - Arm A (RADIATION), Radiotherapy - Arm B (RADIATION). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT03513614?

This trial is sponsored by University Hospital, Basel, Switzerland, which has 10 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT03513614 being conducted?

This trial has 20 study locations across Maryland, North Carolina, Washington, Santa Fe Province. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial