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NCT03495297 · ClinicalTrials.gov registry record · NA

A Randomised Trial of S-ICD Implantation With and Without Defibrillation Testing

A NA study of Ventricular Arrythmia, sponsored by Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA).

Active
Registry status
NA
Development phase
965
Enrollment target
20
Study locations

NCT03495297 is a NA study of Ventricular Arrythmia that is active but no longer recruiting, run by Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA). The registered enrollment target is 965 participants, below the 2,962-participant average among 3 other Ventricular Arrythmia trials with a reported enrollment target (67% lower). The trial reports 20 study locations across 7 states.

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The verdict

NCT03495297, a NA study of Ventricular Arrythmia, is active but no longer recruiting, sponsored by Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA).

ACTIVE NOT RECRUITING
Registry status
NA
Development phase
965 participants
Enrollment target
20
Study locations

Study Summary

This study will test the hypothesis that implantation of a subcutaneous implantable cardioverter defibrillator (S-ICD) without performing a defibrillation test is non-inferior to S-ICD implant with a defibrillation test with regards to the primary endpoint failed first shock in a spontaneous arrhythmia episode when implant position is confirmed with PRAETORIAN score.

Conditions Studied

Interventions

  • PROCEDURE ommitence of defibrillation testing

Study Locations (20)

Other

  • Asklepios Kliniken - Hamburg
  • Universitätsklinikum Schleswig-Holstein - Kiel
  • Universitätsklinikum Schleswig-Holstein, Campus Lübeck - Lübeck
  • Universitätsklinikum Mannheim - Mannheim
  • Universitätsklinikum Würzburg - Würzburg
  • Flevoziekenhuis - Almere Stad
  • Academic Medical Center Amsterdam - Amsterdam
  • OLVG - Amsterdam
  • Albert Schweitzer Ziekenhuis - Dordrecht
  • Catharina Ziekenhuis - Eindhoven
  • UMCG - Groningen
  • Spaarne Gasthuis - Haarlem
  • Medisch Centrum Leeuwarden - Leeuwarden

New York

  • Mount Sinai Beth Israel - New York
  • Icahn School of Medicine at Mount Sinaï - New York

Florida

  • Adventh Health System - Orlando

Georgia

  • Emory University Hospital - Atlanta

Illinois

  • CorVita Science Foundation - Chicago

New Jersey

  • Englewood Hospital and Medical Center - Englewood

Tennessee

  • Erlanger Health System - Chattanooga

Trial Details

FieldValue
Enrollment Target 965 participants
Start Date 2018-05-07
Est. Completion 2025-07
Phase NA

What the Registry Record Tells You About NCT03495297

The ClinicalTrials.gov registry entry for NCT03495297 describes a study currently listed as active not recruiting, categorized as NA. The registered enrollment target is 965 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 2,962-participant average among 3 other Ventricular Arrythmia trials with a reported enrollment target (67% lower). The listed sponsor is Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA), which has 8 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Ventricular Arrythmia appearing as the primary indexed condition, and to 1 intervention - of which ommitence of defibrillation testing is the first listed.

NCT03495297 reports 20 study locations spanning 7 distinct geographic areas - top geographies include Other, New York, Florida.

Frequently Asked Questions

What is clinical trial NCT03495297 about?

NCT03495297 is a clinical study titled "A Randomised Trial of S-ICD Implantation With and Without Defibrillation Testing". This study will test the hypothesis that implantation of a subcutaneous implantable cardioverter defibrillator (S-ICD) without performing a defibrillation test is non-inferior to S-ICD implant with a defibrillation test with regards to the primary endpoint failed first shock in a spontaneous arrhyth...

What is the current status of trial NCT03495297?

This trial is currently active not recruiting. It is a NA study. The enrollment target is 965 participants. The study started on 2018-05-07. Estimated completion is 2025-07.

What conditions does trial NCT03495297 study?

This clinical trial studies the following conditions: Ventricular Arrythmia.

What interventions are being tested in trial NCT03495297?

The interventions under investigation include: ommitence of defibrillation testing (PROCEDURE).

Who is sponsoring clinical trial NCT03495297?

This trial is sponsored by Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA), which has 8 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03495297 being conducted?

This trial has 20 study locations across Florida, Georgia, Illinois, New Jersey, New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.